Branch retinal arterial occlusion treated with intravenous prostaglandin E1 and steroids

Robert D. Steigerwalt, Gianni Belcaro, M. Rosaria Cesarone, Mauro De Angelis, Francesca Romana Florio, Roberto Gattegna, Antonella Pascarella

Research output: Contribution to journalArticlepeer-review


Purpose: To present the use of 6-methylprednisolone IV and prostaglandin E1 IV, a powerful vasodilator of the microcirculation, in the treatment of a branch retinal arterial occlusion. Methods: A 63-year-old man presented with a 3-hour history of a sudden loss of vision in the right eye. On ophthalmic examination, the diagnosis of a superior temporal branch retinal arterial occlusion was made. The patient was immediately given 40 mg of 6-methylprednisolone IV for more than 5 minutes followed by 80 mg of prostaglandin E1 with 2 milliequivalents of potassium IV for more than 3 hours. The same treatment was repeated the following morning. Results: The visual acuity in the right eye improved from 2/10 at presentation to 7/10 at the end of the second day of treatment. Clinically, there was a reduction of the posterior pole edema. Eleven days after treatment, the visual acuity was 9/10 with no retinal edema. Conclusion: Immediate prostaglandin E1 IV and steroids should be considered in cases of recent-onset branch retinal arterial occlusion to restore retinal blood flow and improve visual acuity.

Original languageEnglish
Pages (from-to)355-357
Number of pages3
JournalRetinal Cases and Brief Reports
Issue number4
Publication statusPublished - Sep 2011


  • Branch retinal arterial occlusion (BRAO)
  • Ischemia-reperfusion injury
  • Ocular ischemia
  • Prostaglandin E1(PGE1)

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Branch retinal arterial occlusion treated with intravenous prostaglandin E1 and steroids'. Together they form a unique fingerprint.

Cite this