TY - JOUR
T1 - Breakthrough pain and its treatment
T2 - critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group
AU - Mercadante, Sebastiano
AU - Marchetti, Paolo
AU - Cuomo, Arturo
AU - Mammucari, Massimo
AU - Caraceni, Augusto
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. The choice of fentanyl products should be based on individual clinical conditions.
AB - Controversies exist about the definition and epidemiology of breakthrough cancer pain (BTcP), the pharmacological treatment options, drug dosing, and how to select the medications for BTcP among the new fentanyl products. Existing data were critically evaluated to provide recommendations by an expert group. An algorithm to diagnose BTcP should be used followed by a careful assessment. Fentanyl products provide efficacy and rapidity of action to counteract the temporal pattern of BTcP. The doses of opioids used for background pain should guide the choice of the doses of fentanyl products. The choice of fentanyl products should be based on individual clinical conditions.
KW - Breakthrough pain
KW - Fentanyl
KW - Morphine
KW - Opioids
UR - http://www.scopus.com/inward/record.url?scp=84952874686&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84952874686&partnerID=8YFLogxK
U2 - 10.1007/s00520-015-2951-y
DO - 10.1007/s00520-015-2951-y
M3 - Article
C2 - 26438145
AN - SCOPUS:84952874686
VL - 24
SP - 961
EP - 968
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
SN - 0941-4355
IS - 2
ER -