Breast cancer in the elderly: Detection and treatment modalities in 341 women

L. Repetto, L. Miglietta, M. Costantini, P. Queirolo, D. Cannata, M. Pace, G. Gardin, T. Guido, D. Amoroso, E. Campora, F. Boccardo, R. Rosso

Research output: Contribution to journalArticle

Abstract

Elderly cancer patients are generally excluded from entry to clinical trials and often managed inadequately or based on individual experience. We have retrospectively determined tumor detection modality, diagnostic and staging work-up, delay in referral and therapeutic approaches in 341 women with breast cancer aged over 70 years. Fifty-eight per cent of patients were in the 70-75 group of age. Our data suggest that tumor is detected during medical visit or hospitalization for reasons other than breast cancer in 63.1% elderly women with 74.1% of tumors diagnosed on stage I+II disease; the interval between patient's awareness of a breast nodule and first diagnostic and/or therapeutic intervention was less than 3 months in 51.4% and between 3 and 6 months in 20.7% of patients. Most of our patients received adequate treatment although in 18.6%, 26.8% and 18.2% of stage II, III and IV respectively systemic treatment was not administered after surgery. A large proportion (22.3%) of patients received Halsted mastectomy and only 11.1% conservative surgery. We suggest breast examination should be encouraged, screening program should be extended after the age of 70 years and systemic treatment should be evaluated in elderly patients.

Original languageEnglish
Pages (from-to)1399-1403
Number of pages5
JournalInternational Journal of Oncology
Volume5
Issue number6
Publication statusPublished - 1994

Fingerprint

Breast Neoplasms
Therapeutics
Neoplasms
Breast
Radical Mastectomy
Hospitalization
Referral and Consultation
Age Groups
Clinical Trials

Keywords

  • breast cancer
  • elderly

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Repetto, L., Miglietta, L., Costantini, M., Queirolo, P., Cannata, D., Pace, M., ... Rosso, R. (1994). Breast cancer in the elderly: Detection and treatment modalities in 341 women. International Journal of Oncology, 5(6), 1399-1403.

Breast cancer in the elderly : Detection and treatment modalities in 341 women. / Repetto, L.; Miglietta, L.; Costantini, M.; Queirolo, P.; Cannata, D.; Pace, M.; Gardin, G.; Guido, T.; Amoroso, D.; Campora, E.; Boccardo, F.; Rosso, R.

In: International Journal of Oncology, Vol. 5, No. 6, 1994, p. 1399-1403.

Research output: Contribution to journalArticle

Repetto, L, Miglietta, L, Costantini, M, Queirolo, P, Cannata, D, Pace, M, Gardin, G, Guido, T, Amoroso, D, Campora, E, Boccardo, F & Rosso, R 1994, 'Breast cancer in the elderly: Detection and treatment modalities in 341 women', International Journal of Oncology, vol. 5, no. 6, pp. 1399-1403.
Repetto, L. ; Miglietta, L. ; Costantini, M. ; Queirolo, P. ; Cannata, D. ; Pace, M. ; Gardin, G. ; Guido, T. ; Amoroso, D. ; Campora, E. ; Boccardo, F. ; Rosso, R. / Breast cancer in the elderly : Detection and treatment modalities in 341 women. In: International Journal of Oncology. 1994 ; Vol. 5, No. 6. pp. 1399-1403.
@article{a71fb8c2b44d4a299ea5e005e9faac6e,
title = "Breast cancer in the elderly: Detection and treatment modalities in 341 women",
abstract = "Elderly cancer patients are generally excluded from entry to clinical trials and often managed inadequately or based on individual experience. We have retrospectively determined tumor detection modality, diagnostic and staging work-up, delay in referral and therapeutic approaches in 341 women with breast cancer aged over 70 years. Fifty-eight per cent of patients were in the 70-75 group of age. Our data suggest that tumor is detected during medical visit or hospitalization for reasons other than breast cancer in 63.1{\%} elderly women with 74.1{\%} of tumors diagnosed on stage I+II disease; the interval between patient's awareness of a breast nodule and first diagnostic and/or therapeutic intervention was less than 3 months in 51.4{\%} and between 3 and 6 months in 20.7{\%} of patients. Most of our patients received adequate treatment although in 18.6{\%}, 26.8{\%} and 18.2{\%} of stage II, III and IV respectively systemic treatment was not administered after surgery. A large proportion (22.3{\%}) of patients received Halsted mastectomy and only 11.1{\%} conservative surgery. We suggest breast examination should be encouraged, screening program should be extended after the age of 70 years and systemic treatment should be evaluated in elderly patients.",
keywords = "breast cancer, elderly",
author = "L. Repetto and L. Miglietta and M. Costantini and P. Queirolo and D. Cannata and M. Pace and G. Gardin and T. Guido and D. Amoroso and E. Campora and F. Boccardo and R. Rosso",
year = "1994",
language = "English",
volume = "5",
pages = "1399--1403",
journal = "International Journal of Oncology",
issn = "1019-6439",
publisher = "Spandidos Publications",
number = "6",

}

TY - JOUR

T1 - Breast cancer in the elderly

T2 - Detection and treatment modalities in 341 women

AU - Repetto, L.

AU - Miglietta, L.

AU - Costantini, M.

AU - Queirolo, P.

AU - Cannata, D.

AU - Pace, M.

AU - Gardin, G.

AU - Guido, T.

AU - Amoroso, D.

AU - Campora, E.

AU - Boccardo, F.

AU - Rosso, R.

PY - 1994

Y1 - 1994

N2 - Elderly cancer patients are generally excluded from entry to clinical trials and often managed inadequately or based on individual experience. We have retrospectively determined tumor detection modality, diagnostic and staging work-up, delay in referral and therapeutic approaches in 341 women with breast cancer aged over 70 years. Fifty-eight per cent of patients were in the 70-75 group of age. Our data suggest that tumor is detected during medical visit or hospitalization for reasons other than breast cancer in 63.1% elderly women with 74.1% of tumors diagnosed on stage I+II disease; the interval between patient's awareness of a breast nodule and first diagnostic and/or therapeutic intervention was less than 3 months in 51.4% and between 3 and 6 months in 20.7% of patients. Most of our patients received adequate treatment although in 18.6%, 26.8% and 18.2% of stage II, III and IV respectively systemic treatment was not administered after surgery. A large proportion (22.3%) of patients received Halsted mastectomy and only 11.1% conservative surgery. We suggest breast examination should be encouraged, screening program should be extended after the age of 70 years and systemic treatment should be evaluated in elderly patients.

AB - Elderly cancer patients are generally excluded from entry to clinical trials and often managed inadequately or based on individual experience. We have retrospectively determined tumor detection modality, diagnostic and staging work-up, delay in referral and therapeutic approaches in 341 women with breast cancer aged over 70 years. Fifty-eight per cent of patients were in the 70-75 group of age. Our data suggest that tumor is detected during medical visit or hospitalization for reasons other than breast cancer in 63.1% elderly women with 74.1% of tumors diagnosed on stage I+II disease; the interval between patient's awareness of a breast nodule and first diagnostic and/or therapeutic intervention was less than 3 months in 51.4% and between 3 and 6 months in 20.7% of patients. Most of our patients received adequate treatment although in 18.6%, 26.8% and 18.2% of stage II, III and IV respectively systemic treatment was not administered after surgery. A large proportion (22.3%) of patients received Halsted mastectomy and only 11.1% conservative surgery. We suggest breast examination should be encouraged, screening program should be extended after the age of 70 years and systemic treatment should be evaluated in elderly patients.

KW - breast cancer

KW - elderly

UR - http://www.scopus.com/inward/record.url?scp=0028080991&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028080991&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0028080991

VL - 5

SP - 1399

EP - 1403

JO - International Journal of Oncology

JF - International Journal of Oncology

SN - 1019-6439

IS - 6

ER -