TY - JOUR
T1 - Breast Cancer Metastatic to the Pituitary Gland
T2 - Case Report
AU - Spinelli, Gian Paolo
AU - Lo Russo, Giuseppe
AU - Miele, Evelina
AU - Prinzi, Natalie
AU - Tomao, Federica
AU - Antonelli, Manila
AU - Giangaspero, Felice
AU - Stati, Valeria
AU - Strudel, Martina
AU - Tomao, Silverio
PY - 2012/7/9
Y1 - 2012/7/9
N2 - Background: Metastaseis to the pituitary gland are rare events and usually indicate widespread malignant disease. The lung and the breast are the most common sites of the primary tumour.Moreover this diffusion tends to affects elderly patients. The most frequent symptoms at presentation are diabetes insipidus and visual alterations. Case Presentation: Here we present the case of a 72 year old Caucasian woman treated in 1998 for a breast carcinoma with right supero-external quadrantectomy, radiotherapy, and hormonotherapy. Twelve-years later, she accused bone pain, bilateral progressive visual decline and onset of hypopituitarism. Diagnosis of secondary bone involvement and pituitary metastasis was performed. The description of this case is supported by critical analysis of the clinical and radiological features. Conclusion: The unusual course of the reported disease stresses the importance of intensive follow-up in patients with breast cancer even after many years from diagnosis Our report underlines how diagnosis can be difficult and controversial when relapse occurs at uncommon sites.
AB - Background: Metastaseis to the pituitary gland are rare events and usually indicate widespread malignant disease. The lung and the breast are the most common sites of the primary tumour.Moreover this diffusion tends to affects elderly patients. The most frequent symptoms at presentation are diabetes insipidus and visual alterations. Case Presentation: Here we present the case of a 72 year old Caucasian woman treated in 1998 for a breast carcinoma with right supero-external quadrantectomy, radiotherapy, and hormonotherapy. Twelve-years later, she accused bone pain, bilateral progressive visual decline and onset of hypopituitarism. Diagnosis of secondary bone involvement and pituitary metastasis was performed. The description of this case is supported by critical analysis of the clinical and radiological features. Conclusion: The unusual course of the reported disease stresses the importance of intensive follow-up in patients with breast cancer even after many years from diagnosis Our report underlines how diagnosis can be difficult and controversial when relapse occurs at uncommon sites.
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U2 - 10.1186/1477-7819-10-137
DO - 10.1186/1477-7819-10-137
M3 - Article
C2 - 22776141
AN - SCOPUS:84863527457
SP - 137
JO - World Journal of Surgical Oncology
JF - World Journal of Surgical Oncology
SN - 1477-7819
ER -