Breast cancer screening and diagnosis: A synopsis of the european breast guidelines

Holger J. Schünemann, Donata Lerda, Cecily Quinn, Markus Follmann, Pablo Alonso-Coello, Paolo Giorgi Rossi, Annette Lebeau, Lennarth Nyström, Mireille Broeders, Lydia Ioannidou-Mouzaka, Stephen W. Duffy, Bettina Borisch, Patricia Fitzpatrick, Solveig Hofvind, Xavier Castells, Livia Giordano, Carlos Canelo-Aybar, Sue Warman, Robert Mansel, Francesco SardanelliElena Parmelli, Axel Gräwingholt, Zuleika Saz-Parkinson

Research output: Contribution to journalArticlepeer-review


Description: The European Commission Initiative for Breast Cancer Screening and Diagnosis guidelines (European Breast Guidelines) are coordinated by the European Commission's Joint Research Centre. The target audience for the guidelines includes women, health professionals, and policymakers. Methods: An international guideline panel of 28 multidisciplinary members, including patients, developed questions and corresponding recommendations that were informed by systematic reviews of the evidence conducted between March 2016 and December 2018. GRADE (Grading of Recommendations Assessment, Development and Evaluation) Evidence to Decision frameworks were used to structure the process and minimize the influence of competing interests by enhancing transparency. Questions and recommendations, expressed as strong or conditional, focused on outcomes that matter to women and provided a rating of the certainty of evidence. Recommendations: This synopsis of the European Breast Guidelines provides recommendations regarding organized screening programs for women aged 40 to 75 years who are at average risk. The recommendations address digital mammography screening and the addition of hand-held ultrasonography, automated breast ultrasonography, or magnetic resonance imaging compared with mammography alone. The recommendations also discuss the frequency of screening and inform decision making for women at average risk who are recalled for suspicious lesions or who have high breast density.

Original languageEnglish
JournalAnnals of Internal Medicine
Publication statusE-pub ahead of print - Nov 26 2019

ASJC Scopus subject areas

  • Internal Medicine


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