Abstract
Background: A small but significant proportion of patients with breast cancer (BC) will develop loco-regional recurrence (LRR) after immediate breast reconstruction (IBR). The LRR also varies according to breast cancer subtypes and clinicopathological features. Methods: We studied 1742 consecutive BC patients with IBR between 1997 and 2006. According to St Gallen conference consensus 2011, its BC approximations were applied to classify BC into five subtypes: estrogen receptor (ER) and/or progesterone receptor (PgR) positive, HER2 negative, and low Ki67 (2 cm, body mass index (BMI) ≥25, triple negative and luminal B/HER2 positive subtypes were associated with increased risk of LRR. Conclusion: Luminal B/HER2 positive, triple negative subtypes and BMI ≥25 are independent prognostic factors for risk of LRR after IBR.
| Original language | English |
|---|---|
| Pages (from-to) | 260-265 |
| Number of pages | 6 |
| Journal | European Journal of Surgical Oncology |
| Volume | 39 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2013 |
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Keywords
- Breast cancer
- Breast cancer subtype
- Immediate breast reconstruction
- Local recurrence
- Regional recurrence
- Surgery
ASJC Scopus subject areas
- Oncology
- Surgery
Cite this
Breast cancer subtype approximations and loco-regional recurrence after immediate breast reconstruction. / Kneubil, M. C.; Brollo, J.; Botteri, E.; Curigliano, G.; Rotmensz, N.; Goldhirsch, A.; Lohsiriwat, V.; Manconi, A.; Martella, S.; Santillo, B.; Petit, J. Y.; Rietjens, M.
In: European Journal of Surgical Oncology, Vol. 39, No. 3, 03.2013, p. 260-265.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Breast cancer subtype approximations and loco-regional recurrence after immediate breast reconstruction
AU - Kneubil, M. C.
AU - Brollo, J.
AU - Botteri, E.
AU - Curigliano, G.
AU - Rotmensz, N.
AU - Goldhirsch, A.
AU - Lohsiriwat, V.
AU - Manconi, A.
AU - Martella, S.
AU - Santillo, B.
AU - Petit, J. Y.
AU - Rietjens, M.
PY - 2013/3
Y1 - 2013/3
N2 - Background: A small but significant proportion of patients with breast cancer (BC) will develop loco-regional recurrence (LRR) after immediate breast reconstruction (IBR). The LRR also varies according to breast cancer subtypes and clinicopathological features. Methods: We studied 1742 consecutive BC patients with IBR between 1997 and 2006. According to St Gallen conference consensus 2011, its BC approximations were applied to classify BC into five subtypes: estrogen receptor (ER) and/or progesterone receptor (PgR) positive, HER2 negative, and low Ki67 (2 cm, body mass index (BMI) ≥25, triple negative and luminal B/HER2 positive subtypes were associated with increased risk of LRR. Conclusion: Luminal B/HER2 positive, triple negative subtypes and BMI ≥25 are independent prognostic factors for risk of LRR after IBR.
AB - Background: A small but significant proportion of patients with breast cancer (BC) will develop loco-regional recurrence (LRR) after immediate breast reconstruction (IBR). The LRR also varies according to breast cancer subtypes and clinicopathological features. Methods: We studied 1742 consecutive BC patients with IBR between 1997 and 2006. According to St Gallen conference consensus 2011, its BC approximations were applied to classify BC into five subtypes: estrogen receptor (ER) and/or progesterone receptor (PgR) positive, HER2 negative, and low Ki67 (2 cm, body mass index (BMI) ≥25, triple negative and luminal B/HER2 positive subtypes were associated with increased risk of LRR. Conclusion: Luminal B/HER2 positive, triple negative subtypes and BMI ≥25 are independent prognostic factors for risk of LRR after IBR.
KW - Breast cancer
KW - Breast cancer subtype
KW - Immediate breast reconstruction
KW - Local recurrence
KW - Regional recurrence
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=84874115664&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84874115664&partnerID=8YFLogxK
U2 - 10.1016/j.ejso.2012.12.004
DO - 10.1016/j.ejso.2012.12.004
M3 - Article
C2 - 23313014
AN - SCOPUS:84874115664
VL - 39
SP - 260
EP - 265
JO - European Journal of Surgical Oncology
JF - European Journal of Surgical Oncology
SN - 0748-7983
IS - 3
ER -