Abstract
Background: A small but significant proportion of patients with breast cancer (BC) will develop loco-regional recurrence (LRR) after immediate breast reconstruction (IBR). The LRR also varies according to breast cancer subtypes and clinicopathological features. Methods: We studied 1742 consecutive BC patients with IBR between 1997 and 2006. According to St Gallen conference consensus 2011, its BC approximations were applied to classify BC into five subtypes: estrogen receptor (ER) and/or progesterone receptor (PgR) positive, HER2 negative, and low Ki67 (2 cm, body mass index (BMI) ≥25, triple negative and luminal B/HER2 positive subtypes were associated with increased risk of LRR. Conclusion: Luminal B/HER2 positive, triple negative subtypes and BMI ≥25 are independent prognostic factors for risk of LRR after IBR.
Original language | English |
---|---|
Pages (from-to) | 260-265 |
Number of pages | 6 |
Journal | European Journal of Surgical Oncology |
Volume | 39 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2013 |
Keywords
- Breast cancer
- Breast cancer subtype
- Immediate breast reconstruction
- Local recurrence
- Regional recurrence
- Surgery
ASJC Scopus subject areas
- Oncology
- Surgery