Breast carcinoma metastasizing to the uterus

Metastases from mammary carcinoma represent the principal cause of exitus in 45% of subjects who died from this neoplasia. Even if they are not frequent, uterine metastases from mammary carcinoma are found at autopsy (2-15% according to various authors' reports). In this study, the authors present 17 cases (1 biopsy and 16 autopsy cases) of uterine metastases from breast carcinoma. The histological examination confirms a more frequent involvement of the uterine corpus, with infiltration of the myometrium. When the endometrium is affected, generally the neoplasia infiltrates the stroma, preserving the glandular architecture. In one case, the uterine metastasis was associated with a fibroleiomyoma. The clinical symptomatology (metrorrhagia in 3 of 17 cases) was poor because, as we have said above, generally the neoplasia infiltrates the myometrium.