Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Antonio Toesca, Edoardo Botteri, Matteo Lazzeroni, Jose Vila, Aikaterini Manika, Bettina Ballardini, Francesca Bettarini, Aliana Guerrieri-Gonzaga, Bernardo Bonanni, Nicole Rotmensz, Giuseppe Viale, Paolo Veronesi, Alberto Luini, Umberto Veronesi, Oreste Gentilini

Research output: Contribution to journalArticlepeer-review

Abstract

Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins

Original languageEnglish
Pages (from-to)829-835
Number of pages7
JournalBreast
Volume23
Issue number6
DOIs
Publication statusPublished - Dec 1 2014

Keywords

  • Breast cancer
  • DCIS
  • DIN
  • Ductal carcinoma in situ
  • Radiation therapy

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

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