Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Antonio Toesca; Edoardo Botteri; Matteo Lazzeroni; Jose Vila; Aikaterini Manika; Bettina Ballardini; Francesca Bettarini; Aliana Guerrieri-Gonzaga; Bernardo Bonanni; Nicole Rotmensz; Giuseppe Viale; Paolo Veronesi; Alberto Luini; Umberto Veronesi; Oreste Gentilini

doi:10.1016/j.breast.2014.08.016

Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Antonio Toesca, Edoardo Botteri, Matteo Lazzeroni, Jose Vila, Aikaterini Manika, Bettina Ballardini, Francesca Bettarini, Aliana Guerrieri-Gonzaga, Bernardo Bonanni, Nicole Rotmensz, Giuseppe Viale, Paolo Veronesi, Alberto Luini, Umberto Veronesi, Oreste Gentilini

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article › peer-review

Abstract

Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins

Original language	English
Pages (from-to)	829-835
Number of pages	7
Journal	Breast
Volume	23
Issue number	6
DOIs	https://doi.org/10.1016/j.breast.2014.08.016
Publication status	Published - Dec 1 2014

Keywords

Breast cancer
DCIS
DIN
Ductal carcinoma in situ
Radiation therapy

ASJC Scopus subject areas

Surgery
Medicine(all)

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10.1016/j.breast.2014.08.016

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Toesca, A., Botteri, E., Lazzeroni, M., Vila, J., Manika, A., Ballardini, B., Bettarini, F., Guerrieri-Gonzaga, A., Bonanni, B., Rotmensz, N., Viale, G., Veronesi, P., Luini, A., Veronesi, U., & Gentilini, O. (2014). Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence. Breast, 23(6), 829-835. https://doi.org/10.1016/j.breast.2014.08.016

Toesca, A, Botteri, E, Lazzeroni, M, Vila, J, Manika, A, Ballardini, B, Bettarini, F, Guerrieri-Gonzaga, A , Bonanni, B, Rotmensz, N, Viale, G , Veronesi, P , Luini, A, Veronesi, U & Gentilini, O 2014, 'Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence', Breast, vol. 23, no. 6, pp. 829-835. https://doi.org/10.1016/j.breast.2014.08.016

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abstract = "Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins ",

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T2 - Risk factors for ipsilateral breast tumor recurrence

AU - Toesca, Antonio

AU - Botteri, Edoardo

AU - Lazzeroni, Matteo

AU - Vila, Jose

AU - Manika, Aikaterini

AU - Ballardini, Bettina

AU - Bettarini, Francesca

AU - Guerrieri-Gonzaga, Aliana

AU - Bonanni, Bernardo

AU - Rotmensz, Nicole

AU - Viale, Giuseppe

AU - Veronesi, Paolo

AU - Luini, Alberto

AU - Veronesi, Umberto

AU - Gentilini, Oreste

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins

AB - Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins

KW - Breast cancer

KW - DCIS

KW - DIN

KW - Ductal carcinoma in situ

KW - Radiation therapy

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Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Abstract

Keywords

ASJC Scopus subject areas

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