Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Antonio Toesca; Edoardo Botteri; Matteo Lazzeroni; Jose Vila; Aikaterini Manika; Bettina Ballardini; Francesca Bettarini; Aliana Guerrieri-Gonzaga; Bernardo Bonanni; Nicole Rotmensz; Giuseppe Viale; Paolo Veronesi; Alberto Luini; Umberto Veronesi; Oreste Gentilini

doi:10.1016/j.breast.2014.08.016

Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence

Antonio Toesca, Edoardo Botteri, Matteo Lazzeroni, Jose Vila, Aikaterini Manika, Bettina Ballardini, Francesca Bettarini, Aliana Guerrieri-Gonzaga, Bernardo Bonanni, Nicole Rotmensz, Giuseppe Viale, Paolo Veronesi, Alberto Luini, Umberto Veronesi, Oreste Gentilini

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article

Abstract

Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins

Original language	English
Pages (from-to)	829-835
Number of pages	7
Journal	Breast
Volume	23
Issue number	6
DOIs	https://doi.org/10.1016/j.breast.2014.08.016
Publication status	Published - Dec 1 2014

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Keywords

Breast cancer
DCIS
DIN
Ductal carcinoma in situ
Radiation therapy

ASJC Scopus subject areas

Surgery
Medicine(all)

Cite this

Toesca, A., Botteri, E., Lazzeroni, M., Vila, J., Manika, A., Ballardini, B., Bettarini, F., Guerrieri-Gonzaga, A., Bonanni, B., Rotmensz, N., Viale, G., Veronesi, P., Luini, A., Veronesi, U., & Gentilini, O. (2014). Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence. Breast, 23(6), 829-835. https://doi.org/10.1016/j.breast.2014.08.016

Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia : Risk factors for ipsilateral breast tumor recurrence. / Toesca, Antonio ; Botteri, Edoardo ; Lazzeroni, Matteo; Vila, Jose; Manika, Aikaterini; Ballardini, Bettina; Bettarini, Francesca; Guerrieri-Gonzaga, Aliana ; Bonanni, Bernardo ; Rotmensz, Nicole ; Viale, Giuseppe ; Veronesi, Paolo ; Luini, Alberto; Veronesi, Umberto; Gentilini, Oreste.

In: Breast, Vol. 23, No. 6, 01.12.2014, p. 829-835.

Research output: Contribution to journal › Article

Toesca, A , Botteri, E , Lazzeroni, M, Vila, J, Manika, A, Ballardini, B, Bettarini, F, Guerrieri-Gonzaga, A , Bonanni, B , Rotmensz, N , Viale, G , Veronesi, P , Luini, A, Veronesi, U & Gentilini, O 2014, 'Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia: Risk factors for ipsilateral breast tumor recurrence', Breast, vol. 23, no. 6, pp. 829-835. https://doi.org/10.1016/j.breast.2014.08.016

Toesca, Antonio ; Botteri, Edoardo ; Lazzeroni, Matteo ; Vila, Jose ; Manika, Aikaterini ; Ballardini, Bettina ; Bettarini, Francesca ; Guerrieri-Gonzaga, Aliana ; Bonanni, Bernardo ; Rotmensz, Nicole ; Viale, Giuseppe ; Veronesi, Paolo ; Luini, Alberto ; Veronesi, Umberto ; Gentilini, Oreste. / Breast conservative surgery for well-differentiated ductal intraepithelial neoplasia : Risk factors for ipsilateral breast tumor recurrence. In: Breast. 2014 ; Vol. 23, No. 6. pp. 829-835.

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abstract = "Rational: We retrospectively analyzed 232 patients affected by well differentiated ductal intraepithelial neoplasia (DIN1c or DCIS G1) treated with conservative surgery without adjuvant radiotherapy. Results: 25 invasive and 18 non-invasive local recurrences were observed (median follow-up 80 months; 5-year cumulative incidence: 12.2%). Seven of the 15 young patients (7% (HR 2.33, 95% C.I. 1.20-4.55) and surgical margins ",

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AU - Vila, Jose

AU - Manika, Aikaterini

AU - Ballardini, Bettina

AU - Bettarini, Francesca

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AU - Bonanni, Bernardo

AU - Rotmensz, Nicole

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KW - DIN

KW - Ductal carcinoma in situ

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10.1016/j.breast.2014.08.016