Breast metastases from oligodendroglioma

An unusual extraneural spread in two young women and a review of the literature

E. Mazza, C. Belli, M. Terreni, C. Doglioni, C. Losio, M. Cantore, A. Mambrini, M. Reni

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Extraneural dissemination of oligodendroglioma is rare. Cases of breast metastases have never been described in the literature. Case reports: We report the first two cases of young women with initial diagnosis of anaplastic oligodendroglioma who experienced mammary gland metastases and a review of the literature. Results: Immunohistochemical analysis performed on material from both primary and metastatic sites did not allow to draw any conclusion on possible etiopathogenetic hypothesis. A review of literature yielded 35 cases of extracranial metastatic oligodendroglioma from 1989 to 2012. Conclusion: Though rare, extracranial dissemination from oligodendroglioma may occur not only in long surviving heavily pre-treated patients. The review of literature and these two cases suggest that spread is primarily to bone and then from bone to other organs through hematogenous route mostly due to leptomeningeal or dura mater invasion. Chemotherapy regimens similar to those commonly used for non metastatic oligodendroglioma are recommended for patients with good performance status.

Original languageEnglish
Pages (from-to)564-572
Number of pages9
JournalCritical Reviews in Oncology/Hematology
Volume88
Issue number3
DOIs
Publication statusPublished - Dec 2013

Fingerprint

Oligodendroglioma
Breast
Neoplasm Metastasis
Dura Mater
Human Mammary Glands
Bone and Bones
Drug Therapy

Keywords

  • Brain tumors
  • Breast
  • Metastasis
  • Oligodendroglioma

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Geriatrics and Gerontology

Cite this

Breast metastases from oligodendroglioma : An unusual extraneural spread in two young women and a review of the literature. / Mazza, E.; Belli, C.; Terreni, M.; Doglioni, C.; Losio, C.; Cantore, M.; Mambrini, A.; Reni, M.

In: Critical Reviews in Oncology/Hematology, Vol. 88, No. 3, 12.2013, p. 564-572.

Research output: Contribution to journalArticle

@article{5ffcc8116adc4eb79b7c63e114fbec8a,
title = "Breast metastases from oligodendroglioma: An unusual extraneural spread in two young women and a review of the literature",
abstract = "Background: Extraneural dissemination of oligodendroglioma is rare. Cases of breast metastases have never been described in the literature. Case reports: We report the first two cases of young women with initial diagnosis of anaplastic oligodendroglioma who experienced mammary gland metastases and a review of the literature. Results: Immunohistochemical analysis performed on material from both primary and metastatic sites did not allow to draw any conclusion on possible etiopathogenetic hypothesis. A review of literature yielded 35 cases of extracranial metastatic oligodendroglioma from 1989 to 2012. Conclusion: Though rare, extracranial dissemination from oligodendroglioma may occur not only in long surviving heavily pre-treated patients. The review of literature and these two cases suggest that spread is primarily to bone and then from bone to other organs through hematogenous route mostly due to leptomeningeal or dura mater invasion. Chemotherapy regimens similar to those commonly used for non metastatic oligodendroglioma are recommended for patients with good performance status.",
keywords = "Brain tumors, Breast, Metastasis, Oligodendroglioma",
author = "E. Mazza and C. Belli and M. Terreni and C. Doglioni and C. Losio and M. Cantore and A. Mambrini and M. Reni",
year = "2013",
month = "12",
doi = "10.1016/j.critrevonc.2013.07.010",
language = "English",
volume = "88",
pages = "564--572",
journal = "Critical Reviews in Oncology/Hematology",
issn = "1040-8428",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Breast metastases from oligodendroglioma

T2 - An unusual extraneural spread in two young women and a review of the literature

AU - Mazza, E.

AU - Belli, C.

AU - Terreni, M.

AU - Doglioni, C.

AU - Losio, C.

AU - Cantore, M.

AU - Mambrini, A.

AU - Reni, M.

PY - 2013/12

Y1 - 2013/12

N2 - Background: Extraneural dissemination of oligodendroglioma is rare. Cases of breast metastases have never been described in the literature. Case reports: We report the first two cases of young women with initial diagnosis of anaplastic oligodendroglioma who experienced mammary gland metastases and a review of the literature. Results: Immunohistochemical analysis performed on material from both primary and metastatic sites did not allow to draw any conclusion on possible etiopathogenetic hypothesis. A review of literature yielded 35 cases of extracranial metastatic oligodendroglioma from 1989 to 2012. Conclusion: Though rare, extracranial dissemination from oligodendroglioma may occur not only in long surviving heavily pre-treated patients. The review of literature and these two cases suggest that spread is primarily to bone and then from bone to other organs through hematogenous route mostly due to leptomeningeal or dura mater invasion. Chemotherapy regimens similar to those commonly used for non metastatic oligodendroglioma are recommended for patients with good performance status.

AB - Background: Extraneural dissemination of oligodendroglioma is rare. Cases of breast metastases have never been described in the literature. Case reports: We report the first two cases of young women with initial diagnosis of anaplastic oligodendroglioma who experienced mammary gland metastases and a review of the literature. Results: Immunohistochemical analysis performed on material from both primary and metastatic sites did not allow to draw any conclusion on possible etiopathogenetic hypothesis. A review of literature yielded 35 cases of extracranial metastatic oligodendroglioma from 1989 to 2012. Conclusion: Though rare, extracranial dissemination from oligodendroglioma may occur not only in long surviving heavily pre-treated patients. The review of literature and these two cases suggest that spread is primarily to bone and then from bone to other organs through hematogenous route mostly due to leptomeningeal or dura mater invasion. Chemotherapy regimens similar to those commonly used for non metastatic oligodendroglioma are recommended for patients with good performance status.

KW - Brain tumors

KW - Breast

KW - Metastasis

KW - Oligodendroglioma

UR - http://www.scopus.com/inward/record.url?scp=84888304443&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888304443&partnerID=8YFLogxK

U2 - 10.1016/j.critrevonc.2013.07.010

DO - 10.1016/j.critrevonc.2013.07.010

M3 - Article

VL - 88

SP - 564

EP - 572

JO - Critical Reviews in Oncology/Hematology

JF - Critical Reviews in Oncology/Hematology

SN - 1040-8428

IS - 3

ER -