Brescia Early Defibrillation Study: A rural and urban experience with automated external defibrillators

Tania Bordonali, Antonio Curnis, Paolo Marzollo, Riccardo Cappato, Zang Feng, Sun Lei Lei, Franco Naccarella

Research output: Contribution to journalArticlepeer-review


Integrating defibrillation by non medical personnel within existing resuscitation programmes has met conflicting results. The recent development in AED technology has enabled the potential use of these devices by layperson and volunteers integrating them with local emergency medical service (EMS) system. However, there are few data on the outcomes of cardiac arrest (CA) victims when the defibrillation capability of broad and urban territories is fully operated by non medical personnel. From July 2000 to June 2002 after a completation of a training and certification process involving 2 186 volunteers and layperson a diffuse deployment of automated external defribrillators (AEDs) (54 devices) was introduced in the County of Brescia, Italy (4 826 Km2) (population 1 112 628). The primary end point was 1-year survival free from neurological impairment. Survival rate increased from 0.9% (95% CI 0.4-1.8%) in period before Brescia Early Defibrillation Study (BEDS) (June 1997-May 1999) to 3.0% (95% CI 1.7-4.3%) in prospective phase of study (p=0.024). Increase of survival was noted both in urban [from 1.4% (95% CI 0.4-3.4%) to 4 (95% CI 2.0-6.9%) p=0.024] and in the rural territory [from 0.5% (95% CI 0.1-1.6%) to 2.5% (95% CI 1.3-4.2%) p=0.013]. The results of BED study provide an evidence as the integration of EMS system with the diffuse implementation of AEDs fully operated by trained volunteers and laypersons within a broad environment is associated with a improvement in long-term survival of CA victims.

Original languageEnglish
Pages (from-to)38-44
Number of pages7
JournalMediterranean Journal of Pacing and Electrophysiology
Issue number1-2
Publication statusPublished - Jan 2008


  • Automated external Defibrillator
  • Brescia Early Defibrillation Study
  • Out-of-Hospital cardiac arrest

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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