Bridge to Lung Transplantation by Venovenous Extracorporeal Membrane Oxygenation: A Lesson Learned on the First Four Cases

M. Nosotti, L. Rosso, A. Palleschi, A. Lissoni, S. Crotti, C. Marenghi, C. Colombo, D. Costantini, L. Santambrogio

Research output: Contribution to journalArticlepeer-review

Abstract

Extracorporeal membrane oxygenation (ECMO) is the only therapeutic option for patients with ventilation-refractory hypercapnia while awaiting lung transplantation. Moreover, there is increasing success using ECMO for definitive respiratory failure in formerly healthy patients. This report describes the use of membrane oxygenation as a bridge to lung transplantation in 2 patients on the waiting list and in 2 previously healthy patients. Our experience showed that coagulation management, critical illness myopathy, and psychological disorders were the most critical problems. One patient died at 2 days after transplantation, 1 at 3 months, and 2 returned to their pretransplantation activities. We concluded that ECMO is an adequate bridge to lung transplantation but, especially in formerly healthy patients, an awake procedure is advisable for a successful outcome.

Original languageEnglish
Pages (from-to)1259-1261
Number of pages3
JournalTransplantation Proceedings
Volume42
Issue number4
DOIs
Publication statusPublished - May 2010

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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