Bridging the gap between hypertrabeculation phenotype, noncompaction phenotype and left ventricular noncompaction cardiomyopathy

Vittoria Vergani, Davide Lazzeroni, Giovanni Peretto

Research output: Contribution to journalArticlepeer-review

Abstract

Left ventricular noncompaction (LVNC) is an increasingly recognised cardiomyopathy characterised by excessive trabeculation and deep intertrabecular recesses in direct communication with the left ventricular cavity. In LVNC, hypertrabeculation has been associated with heart failure, ventricular arrhythmia, and systemic thromboembolism. However, hypertrabeculation alone is not sufficient to define a subject as at risk for such complications and thus should not be sufficient to diagnose LVNC. Despite several studies having investigated parameters to predict adverse cardiovascular events, physicians have no effective tools to differentiate between clinically silent hypertrabeculation and LVNC. The aim of this paper was to review literature on LVNC diagnostic criteria and to provide an easy and accessible diagnostic algorithm to distinguish between hypertrabeculation phenotype, non-compaction phenotype and LVNC cardiomyopathy.

Original languageEnglish
Pages (from-to)192-199
Number of pages8
JournalJournal of cardiovascular medicine (Hagerstown, Md.)
Volume21
Issue number3
DOIs
Publication statusPublished - Mar 2020

Fingerprint

Dive into the research topics of 'Bridging the gap between hypertrabeculation phenotype, noncompaction phenotype and left ventricular noncompaction cardiomyopathy'. Together they form a unique fingerprint.

Cite this