Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head

M A Cardinali, Dante Dallari, Marco Govoni, Cesare Stagni, Federico Marmi, Matilde Tschon, Silvia Brogini, D Fioretto, A Morresi

Research output: Contribution to journalArticle

Abstract

Brillouin micro-spectroscopy is applied for investigating the mechanical properties of bone and cartilage tissues of a human femoral head. Distinctive mechanical properties of the cartilage surface, subchondral and trabecular bone are reported, with marked heterogeneities at both micrometric and millimetric length scales. A ubiquitous soft component is reported for the first time, characterized by a longitudinal modulus of about 4.3 GPa, possibly related to the amorphous phase of the bone. This phase is mixed, at micrometric scales, with a harder component, ascribed to mineralized collagen fibrils, characterized by a longitudinal modulus ranging between 16 and 25 GPa.

Original languageEnglish
Pages (from-to)2606-2611
Number of pages6
JournalBiomedical Optics Express
Volume10
Issue number5
DOIs
Publication statusPublished - Apr 29 2019

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cartilage
Articular Cartilage
Thigh
bones
Cartilage
Spectrum Analysis
Bone and Bones
Surface Properties
mechanical properties
spectroscopy
Collagen
collagens
Cancellous Bone

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Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head. / Cardinali, M A; Dallari, Dante; Govoni, Marco; Stagni, Cesare; Marmi, Federico; Tschon, Matilde; Brogini, Silvia; Fioretto, D; Morresi, A.

In: Biomedical Optics Express, Vol. 10, No. 5, 29.04.2019, p. 2606-2611.

Research output: Contribution to journalArticle

Cardinali, M A ; Dallari, Dante ; Govoni, Marco ; Stagni, Cesare ; Marmi, Federico ; Tschon, Matilde ; Brogini, Silvia ; Fioretto, D ; Morresi, A. / Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head. In: Biomedical Optics Express. 2019 ; Vol. 10, No. 5. pp. 2606-2611.
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AU - Marmi, Federico

AU - Tschon, Matilde

AU - Brogini, Silvia

AU - Fioretto, D

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