Bronchial and bronchoalveolar lavage after allergen challenge in atopic patients

E. Crimi, S. Lantero, S. Oddera, M. Bonavia, P. Crimi, P. Gianiorio, V. Brusasco, G. A. Rossi

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty patients with allergic rhinitis and/or asthma sensitised to Dermatopha- goides pteronyssinus were studied. On two consecutive days they underwent methacholine challenge and allergen bronchial challenge. 72 h after allergen challenge, fibreoptic bronchoscopy with bronchial (BL) and bronchoalveolar (BAL) lavage was performed. Specific IgE antibodies were measured both in serum and in BL. from 14 patients. Both BAL and BL cell differentials were similar in patients with isolated early response to allergen and in patients with dual response. Patients with dual response to allergen showed higher levels of antigen specific IgE antibodies in BL than patients with isolated early response, while IgE levels in serum were similar in the two groups.

Original languageEnglish
Pages (from-to)9-11
Number of pages3
JournalRespiration
Volume59
DOIs
Publication statusPublished - 1992

Keywords

  • Allergen challenge
  • Atopy
  • Bronchial lavage
  • Bronchoalveolar lavage
  • Late asthmatic reaction
  • Specific IgE

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Physiology

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