Bronchiolitis obliterans organizing pneumonia. An early complication of therapy for Hodgkin's disease

G. A. Rossi, E. Castagnola, E. Viscardi, C. Gambini, M. Occhi, C. Granata, P. Franzone, B. De Bernardi

Research output: Contribution to journalArticlepeer-review

Abstract

A 13-year-old girl treated for Hodgkin's disease developed asymptomatic pulmonary infiltrates at an early phase of a chemotherapy protocol combining COOP and ABV. The histological diagnosis was of bronchiolitis obliterans organizing pneumonia (BOOP). In the two weeks following surgery the infiltrates disappeared spontaneously. The patient restarted and completed the chemotherapy regimen with dacarbazine substituted for bleomycin. No further complications occurred and she is presently disease-free 27 months from diagnosis. The possible relations between the underlying malignant disease, side effects of cytotoxic drugs and unidentified infectious agents are discussed.

Original languageEnglish
Pages (from-to)339-345
Number of pages7
JournalInternational Journal of Pediatric Hematology/Oncology
Volume6
Issue number5
Publication statusPublished - 2000

Keywords

  • Bleomycin
  • Bronchiolitis obliterans organizing pneumonia
  • Hodgkin's disease

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Pediatrics, Perinatology, and Child Health

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