TY - JOUR
T1 - Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines
AU - Battistini, E.
AU - Dini, G.
AU - Savioli, C.
AU - Morando, A.
AU - Gandolfo, A.
AU - Kotitsa, Z.
AU - Garaventa, A.
AU - Rossi, G. A.
PY - 1997/5
Y1 - 1997/5
N2 - Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinico-pathological entity with well-defined diagnostic criteria, which can be idiopathic or produced by a variety of biological processes. We describe the occurrence of BOOP in three children, one with acute lymphoblastic leukaemia and two with acute promyelocytic leukaemia. In the three patients, BOOP developed 10-20 days after a course of therapy with cytosine arabinoside and anthracyclines. The possible relationship between the small conducting airway lesions, lung toxic reaction to the drugs and/or nonidentified infectious agents are discussed.
AB - Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinico-pathological entity with well-defined diagnostic criteria, which can be idiopathic or produced by a variety of biological processes. We describe the occurrence of BOOP in three children, one with acute lymphoblastic leukaemia and two with acute promyelocytic leukaemia. In the three patients, BOOP developed 10-20 days after a course of therapy with cytosine arabinoside and anthracyclines. The possible relationship between the small conducting airway lesions, lung toxic reaction to the drugs and/or nonidentified infectious agents are discussed.
KW - anthracyclines
KW - bronchiolitis obliterans organizing pneumonia
KW - cytosine arabinoside
KW - interstitial lung fibrosis
KW - leukaemia
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M3 - Article
C2 - 9163667
AN - SCOPUS:0030908715
VL - 10
SP - 1187
EP - 1190
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 5
ER -