Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines

E. Battistini, G. Dini, C. Savioli, A. Morando, A. Gandolfo, Z. Kotitsa, A. Garaventa, G. A. Rossi

Research output: Contribution to journalArticle

Abstract

Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinico-pathological entity with well-defined diagnostic criteria, which can be idiopathic or produced by a variety of biological processes. We describe the occurrence of BOOP in three children, one with acute lymphoblastic leukaemia and two with acute promyelocytic leukaemia. In the three patients, BOOP developed 10-20 days after a course of therapy with cytosine arabinoside and anthracyclines. The possible relationship between the small conducting airway lesions, lung toxic reaction to the drugs and/or nonidentified infectious agents are discussed.

Original languageEnglish
Pages (from-to)1187-1190
Number of pages4
JournalEuropean Respiratory Journal
Volume10
Issue number5
Publication statusPublished - May 1997

Keywords

  • anthracyclines
  • bronchiolitis obliterans organizing pneumonia
  • cytosine arabinoside
  • interstitial lung fibrosis
  • leukaemia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Battistini, E., Dini, G., Savioli, C., Morando, A., Gandolfo, A., Kotitsa, Z., Garaventa, A., & Rossi, G. A. (1997). Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines. European Respiratory Journal, 10(5), 1187-1190.