TY - JOUR
T1 - "Bubble-like" lung metastases in osteosarcoma patients
AU - Briccoli, Antonio
AU - Rocca, Michele
AU - Salone, Maria Cristina
AU - Di Fiore, Maria
AU - Vanel, Daniel
AU - Balladelli, Alba
AU - Alberghini, Marco
PY - 2009/7
Y1 - 2009/7
N2 - Purpose: Cavitation of pulmonary metastases have been reported by several authors either as a spontaneous phenomenon or as a consequence of chemotherapy. We present two cases, with this type of image in follow-up, and 20-45 months after the end of treatment. This was the first sign of pulmonary metastases. Results: Two patients with osteogenic sarcoma developed radiological evidence of pulmonary "bubble-like" cavitation several years following completion of chemotherapy. In one patient the "bubble-like" cavitation transformed into a solid nodule. Both patients had surgical resections of all pulmonary lesions, and histology confirmed presence of viable osteosarcoma metastases. Conclusion: The two cases suggest that onset of "bubble-like" cavitation in lung parenchyma of osteosarcoma patients may be the first sign of pulmonary metastases.
AB - Purpose: Cavitation of pulmonary metastases have been reported by several authors either as a spontaneous phenomenon or as a consequence of chemotherapy. We present two cases, with this type of image in follow-up, and 20-45 months after the end of treatment. This was the first sign of pulmonary metastases. Results: Two patients with osteogenic sarcoma developed radiological evidence of pulmonary "bubble-like" cavitation several years following completion of chemotherapy. In one patient the "bubble-like" cavitation transformed into a solid nodule. Both patients had surgical resections of all pulmonary lesions, and histology confirmed presence of viable osteosarcoma metastases. Conclusion: The two cases suggest that onset of "bubble-like" cavitation in lung parenchyma of osteosarcoma patients may be the first sign of pulmonary metastases.
KW - Cavitary metastasis/lung
KW - Computed tomography
KW - Osteosarcoma
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U2 - 10.1016/j.ejrad.2008.03.001
DO - 10.1016/j.ejrad.2008.03.001
M3 - Article
C2 - 18406558
AN - SCOPUS:67649171709
VL - 71
SP - 144
EP - 146
JO - European Journal of Radiology
JF - European Journal of Radiology
SN - 0720-048X
IS - 1
ER -