Bulky mesonephric adenocarcinoma of the uterine cervix treated with neoadjuvant chemotherapy and radical surgery: Report of the first case

Antonino Ditto, Fabio Martinelli, Giorgio Bogani, Maria L. Gasparri, Violante Di Donato, Biagio Paolini, Maria L. Carcangiu, Domenica Lorusso, Francesco Raspagliesi

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1 Citation (Scopus)

Abstract

Aims and background: Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available. Methods: We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery. Conclusions: Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.

Original languageEnglish
Pages (from-to)S82-S83
JournalTumori
Volume102
DOIs
Publication statusPublished - Nov 1 2016

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Cervix Uteri
Adenocarcinoma
Drug Therapy
Obstetrics
Neoplasms
Therapeutics

Keywords

  • Advanced stage
  • Cervical carcinoma
  • Mesonephric adenocarcinoma
  • Neoadjuvant chemotherapy

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Cancer Research

Cite this

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title = "Bulky mesonephric adenocarcinoma of the uterine cervix treated with neoadjuvant chemotherapy and radical surgery: Report of the first case",
abstract = "Aims and background: Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available. Methods: We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery. Conclusions: Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.",
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author = "Antonino Ditto and Fabio Martinelli and Giorgio Bogani and Gasparri, {Maria L.} and {Di Donato}, Violante and Biagio Paolini and Carcangiu, {Maria L.} and Domenica Lorusso and Francesco Raspagliesi",
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T1 - Bulky mesonephric adenocarcinoma of the uterine cervix treated with neoadjuvant chemotherapy and radical surgery

T2 - Report of the first case

AU - Ditto, Antonino

AU - Martinelli, Fabio

AU - Bogani, Giorgio

AU - Gasparri, Maria L.

AU - Di Donato, Violante

AU - Paolini, Biagio

AU - Carcangiu, Maria L.

AU - Lorusso, Domenica

AU - Raspagliesi, Francesco

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Aims and background: Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available. Methods: We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery. Conclusions: Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.

AB - Aims and background: Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available. Methods: We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery. Conclusions: Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.

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KW - Cervical carcinoma

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KW - Neoadjuvant chemotherapy

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