Bullous extragenital lesions of lichen sclerosus et atrophicus are rare and have to be distinguished from bullous lesions of morphoea guttata. The bullae are intradermal and related to severe edema of the papillary dermis; they are often recalcitrant to the treatment. The authors report a case of bullous lichen sclerosus et atrophicus in a 19-year-old female. Clinical lesions, first localized on the external genitalia, extended later over almost the entire surface of the skin. On the trunk some lesions developed bullous areas. A prompt resolution of the bullous lesions followed treatment with systemic cyclosporine (3 mg/kg/die). No new bullae appeared and the patient remained free of lesions when the drug was stopped four months later. Extragenital and genital nonbollous lesions were unchanged. Although in the present case a successful management was obtained with cyclosporine, further experience is necessary to confirm this drug as an alternative therapy of bullous lesions of lichen sclerosus et atrophicus.
|Translated title of the contribution||Bullous lichen sclerosus et atrophicus. Treatment with oral cyclosporin|
|Number of pages||4|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1994|
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