Abstract

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).

Original languageEnglish
Pages (from-to)305-315
Number of pages11
JournalGiornale Italiano di Dermatologia e Venereologia
Volume153
Issue number3
DOIs
Publication statusPublished - Jun 1 2018

Fingerprint

Venereology
Bullous Pemphigoid
Dermatology
Guidelines
Blister
Prurigo
Nervous System Diseases
Legislation
Skin Diseases
Mucous Membrane
Quality of Life
Pharmacology
Morbidity
Therapeutics

Keywords

  • Bullous pemphigoid
  • Guideline
  • Quality of life
  • Rare diseases

ASJC Scopus subject areas

  • Dermatology

Cite this

Bullous pemphigoid : Italian guidelines adapted from the EDF/EADV guidelines. / Cutaneous Immunology group of SIDeMaST.

In: Giornale Italiano di Dermatologia e Venereologia, Vol. 153, No. 3, 01.06.2018, p. 305-315.

Research output: Contribution to journalReview article

Cutaneous Immunology group of SIDeMaST. / Bullous pemphigoid : Italian guidelines adapted from the EDF/EADV guidelines. In: Giornale Italiano di Dermatologia e Venereologia. 2018 ; Vol. 153, No. 3. pp. 305-315.
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abstract = "Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20{\%} of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).",
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AU - Dattola, Annunziata

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AU - Di Lernia, Vito

AU - Di Zenzo, Giovanni M.

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N2 - Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).

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