Burden of Infantile Hemangioma on Family: An International Observational Cross-Sectional Study

Christine Cazeau, Francine Blei, María del Rosario Fátima Gonzáles Hermosa, Riccardo Cavalli, Olivia Boccara, Regina Fölster-Holst, Gilles Berdeaux, Alain Delarue, Jean Jacques Voisard

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background/Objectives: Infantile hemangioma (IH) is the most frequent benign tumor of infancy resulting from vascular proliferation. Data regarding the burden on families of children with IHs are limited. This study aimed to characterize IHs and provide a comprehensive evaluation of the burden of IHs on parents of children requiring systemic treatment in the United States and Europe. Methods: This noninterventional cross-sectional study included infants with newly diagnosed IH requiring systemic treatment. A parent or family member completed two questionnaires (Family Member questionnaire; Hemangioma Family Burden [HFB] questionnaire). Results: A total of 693 individuals were evaluable in five countries. IHs were observed in more girls than boys (66%–83% female) and the mean age at inclusion was 0.44 to 1.4 years. Approximately half of patients had superficial IHs, approximately 70% of cases affected the head, and approximately 80% of cases were moderate or severe. Most patients received propranolol treatment. Their child's IH affected more than 70% of parents in each country, but fewer than 10% were offered psychological support. Approximately half of all parents reported that their child's IH affected their professional life. The global HFB score was significantly (p < 0.001) greater with greater IH severity. More than 90% of parents in each country were satisfied with the care of their child's disease. Conclusions: This international study using the validated HFB questionnaire provides further insight into the burden of IH and highlights potential areas for future focus in assisting families with affected children.

Original languageEnglish
Pages (from-to)295-302
Number of pages8
JournalPediatric Dermatology
Volume34
Issue number3
DOIs
Publication statusPublished - May 1 2017

Fingerprint

Hemangioma
Cross-Sectional Studies
Parents
Child Care
Propranolol
Blood Vessels
Therapeutics
Head
Psychology
Surveys and Questionnaires

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

Cazeau, C., Blei, F., Gonzáles Hermosa, M. D. R. F., Cavalli, R., Boccara, O., Fölster-Holst, R., ... Voisard, J. J. (2017). Burden of Infantile Hemangioma on Family: An International Observational Cross-Sectional Study. Pediatric Dermatology, 34(3), 295-302. https://doi.org/10.1111/pde.13133

Burden of Infantile Hemangioma on Family : An International Observational Cross-Sectional Study. / Cazeau, Christine; Blei, Francine; Gonzáles Hermosa, María del Rosario Fátima; Cavalli, Riccardo; Boccara, Olivia; Fölster-Holst, Regina; Berdeaux, Gilles; Delarue, Alain; Voisard, Jean Jacques.

In: Pediatric Dermatology, Vol. 34, No. 3, 01.05.2017, p. 295-302.

Research output: Contribution to journalArticle

Cazeau, C, Blei, F, Gonzáles Hermosa, MDRF, Cavalli, R, Boccara, O, Fölster-Holst, R, Berdeaux, G, Delarue, A & Voisard, JJ 2017, 'Burden of Infantile Hemangioma on Family: An International Observational Cross-Sectional Study', Pediatric Dermatology, vol. 34, no. 3, pp. 295-302. https://doi.org/10.1111/pde.13133
Cazeau C, Blei F, Gonzáles Hermosa MDRF, Cavalli R, Boccara O, Fölster-Holst R et al. Burden of Infantile Hemangioma on Family: An International Observational Cross-Sectional Study. Pediatric Dermatology. 2017 May 1;34(3):295-302. https://doi.org/10.1111/pde.13133
Cazeau, Christine ; Blei, Francine ; Gonzáles Hermosa, María del Rosario Fátima ; Cavalli, Riccardo ; Boccara, Olivia ; Fölster-Holst, Regina ; Berdeaux, Gilles ; Delarue, Alain ; Voisard, Jean Jacques. / Burden of Infantile Hemangioma on Family : An International Observational Cross-Sectional Study. In: Pediatric Dermatology. 2017 ; Vol. 34, No. 3. pp. 295-302.
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