Burkitt's like lymphoma in patients with and without hiv infection a report of 33 patients from north-east Italy

Emanuela Vaccher, Umberto Tirelli

Research output: Contribution to journalArticle

Abstract

With the aim of comparing the clinical features of Burkitt's like lymphoma (BL) in HIV-infected patients and in the general population, we retrospectively analyzed 35 patients with HIV-positive non-Hodgkin's lymphoma (NHL) and 535 patients with HIV-negative NHL, from 1985 to 1990. A total of 33 patients with BL were diagnosed at our institute: 18 without and 15 with HIV infection; 3.3% and 43% of all HIV-seronegative and HIV-seropositive NHL respectively. No significant differences were found between these two series concerning clinical features, with the exception of peripheral adenopathy that was more common in the HIV infected patients (p = 0.05). In both groups BL was characterized by advanced stage and high incidence of bone marrow and gastrointestinal involvement. Response rate was lower in the HIV-positive patients, but the difference was not significant. No relevant differences in the toxicity after chemotherapy were observed. The median survival in the HIV-infected patients was lower (7 months) than in the other group (14 months), with borderline statistical significance (p = 0.06).

Original languageEnglish
Pages (from-to)507-511
Number of pages5
JournalActa Oncologica
Volume33
Issue number5
DOIs
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

Fingerprint Dive into the research topics of 'Burkitt's like lymphoma in patients with and without hiv infection a report of 33 patients from north-east Italy'. Together they form a unique fingerprint.

  • Cite this