Abstract
We describe a patient with severe combined immunodeficiency because of aberrations in adenosine deaminase (ADA) who despite adequate replacement with polyethylene glycol-linked ADA (PEG-ADA) for 13 years developed Burkitt's lymphoma. Although treatment corrected the metabolic abnormalities caused by ADA deficiency, it failed to fully restore cellular immunity.
| Original language | English |
|---|---|
| Pages (from-to) | 93-95 |
| Number of pages | 3 |
| Journal | Journal of Pediatrics |
| Volume | 151 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2007 |
Fingerprint
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Burkitt's Lymphoma in a Patient with Adenosine Deaminase Deficiency-Severe Combined Immunodeficiency Treated with Polyethylene Glycol-Adenosine Deaminase. / Husain, Maitham; Grunebaum, Eyal; Naqvi, Ahmed; Atkinson, Adelle; Ngan, Bo Y.; Aiuti, Alessandro; Roifman, Chaim M.
In: Journal of Pediatrics, Vol. 151, No. 1, 07.2007, p. 93-95.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Burkitt's Lymphoma in a Patient with Adenosine Deaminase Deficiency-Severe Combined Immunodeficiency Treated with Polyethylene Glycol-Adenosine Deaminase
AU - Husain, Maitham
AU - Grunebaum, Eyal
AU - Naqvi, Ahmed
AU - Atkinson, Adelle
AU - Ngan, Bo Y.
AU - Aiuti, Alessandro
AU - Roifman, Chaim M.
PY - 2007/7
Y1 - 2007/7
N2 - We describe a patient with severe combined immunodeficiency because of aberrations in adenosine deaminase (ADA) who despite adequate replacement with polyethylene glycol-linked ADA (PEG-ADA) for 13 years developed Burkitt's lymphoma. Although treatment corrected the metabolic abnormalities caused by ADA deficiency, it failed to fully restore cellular immunity.
AB - We describe a patient with severe combined immunodeficiency because of aberrations in adenosine deaminase (ADA) who despite adequate replacement with polyethylene glycol-linked ADA (PEG-ADA) for 13 years developed Burkitt's lymphoma. Although treatment corrected the metabolic abnormalities caused by ADA deficiency, it failed to fully restore cellular immunity.
UR - http://www.scopus.com/inward/record.url?scp=34250679783&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34250679783&partnerID=8YFLogxK
U2 - 10.1016/j.jpeds.2007.03.059
DO - 10.1016/j.jpeds.2007.03.059
M3 - Article
VL - 151
SP - 93
EP - 95
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 1
ER -