Burst activity and heart rhythm modulation in the sympathetic outflow to the heart

G. Baselli, C. Falcomatà, F. Gelain, S. Cerutti, M. Massimini, N. Montano, A. Porta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In 13 decerebrate, artificially ventilated cats preganglionic sympathetic outflow to the heart was recorded with ECG and ventilation signal. A novel algorithm was implemented that extracts weighted events representing burst occurrences and their size. A multiple threshold strategy was used to separate bursts. Weighted events yielded count signals. Spectral analysis of the count signal revealed a predominance of a discharge synchronous to heart beat at cardiac frequency (CF≅3 Hz), a ventilation rhythm at the high frequency (HF≅0.3 Hz) of beat-to-beat variability, and in 9 of 13 cats a Mayer's wave lower frequency (LF). The CF component was ∼50% larger in power than both HF and also LF (when present). Spectral analysis at increasing count levels (i.e., with only the events with a weight ≥ the considered level) indicated that all rhythms were carried by burst activity and its modulations. A modulation index of HF over CF, MIHF/CF was extracted from dynamic (i.e., ventilation cycle by ventilation cycle) folded histograms of counts. MIHF/CF was significantly higher in the group without LF (0.65±0.20, mean±SD, n=4) than in that with LF (0.41±0.07, n=9). Burst activity can be a key element in the interactions between cardiovascular variability rhythms.

Original languageEnglish
Title of host publicationAnnual Reports of the Research Reactor Institute, Kyoto University
Pages582-584
Number of pages3
Volume1
Publication statusPublished - 2001
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: Oct 25 2001Oct 28 2001

Other

Other23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryTurkey
CityIstanbul
Period10/25/0110/28/01

Fingerprint

Ventilation
Modulation
Spectrum analysis
Electrocardiography

Keywords

  • Beat-to-beat variability
  • Burst activity
  • Cardiac rhythm
  • Sympathetic outflow

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Mechanical Engineering

Cite this

Baselli, G., Falcomatà, C., Gelain, F., Cerutti, S., Massimini, M., Montano, N., & Porta, A. (2001). Burst activity and heart rhythm modulation in the sympathetic outflow to the heart. In Annual Reports of the Research Reactor Institute, Kyoto University (Vol. 1, pp. 582-584)

Burst activity and heart rhythm modulation in the sympathetic outflow to the heart. / Baselli, G.; Falcomatà, C.; Gelain, F.; Cerutti, S.; Massimini, M.; Montano, N.; Porta, A.

Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. p. 582-584.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Baselli, G, Falcomatà, C, Gelain, F, Cerutti, S, Massimini, M, Montano, N & Porta, A 2001, Burst activity and heart rhythm modulation in the sympathetic outflow to the heart. in Annual Reports of the Research Reactor Institute, Kyoto University. vol. 1, pp. 582-584, 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey, 10/25/01.
Baselli G, Falcomatà C, Gelain F, Cerutti S, Massimini M, Montano N et al. Burst activity and heart rhythm modulation in the sympathetic outflow to the heart. In Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1. 2001. p. 582-584
Baselli, G. ; Falcomatà, C. ; Gelain, F. ; Cerutti, S. ; Massimini, M. ; Montano, N. ; Porta, A. / Burst activity and heart rhythm modulation in the sympathetic outflow to the heart. Annual Reports of the Research Reactor Institute, Kyoto University. Vol. 1 2001. pp. 582-584
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