Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function.

C. Eftimiadi, S. Valente, S. Mangiante, M. Ferrarini

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The effect on B-lymphocytes of butyric acid, a metabolic by-product formed by selected anaerobic bacteria of the subgingival plaque and present in mM amounts in the crevicular fluid of patients affected by adult periodontitis was investigated. A dose-dependent inhibition of both mitogenesis and Ig production in B-cells challenged with formalinized Staphylococcus aureus, strain Cowan I (SAC), was observed. A role of this molecule in the downregulation of the local immune response in periodontal patients is proposed.

Original languageEnglish
Pages (from-to)445-447
Number of pages3
JournalMinerva Stomatologica
Volume44
Issue number10
Publication statusPublished - Oct 1995

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Butyric Acid
Anaerobic Bacteria
B-Lymphocytes
Chronic Periodontitis
Staphylococcus aureus
Down-Regulation

Cite this

Eftimiadi, C., Valente, S., Mangiante, S., & Ferrarini, M. (1995). Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. Minerva Stomatologica, 44(10), 445-447.

Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. / Eftimiadi, C.; Valente, S.; Mangiante, S.; Ferrarini, M.

In: Minerva Stomatologica, Vol. 44, No. 10, 10.1995, p. 445-447.

Research output: Contribution to journalArticle

Eftimiadi, C, Valente, S, Mangiante, S & Ferrarini, M 1995, 'Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function.', Minerva Stomatologica, vol. 44, no. 10, pp. 445-447.
Eftimiadi C, Valente S, Mangiante S, Ferrarini M. Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. Minerva Stomatologica. 1995 Oct;44(10):445-447.
Eftimiadi, C. ; Valente, S. ; Mangiante, S. ; Ferrarini, M. / Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. In: Minerva Stomatologica. 1995 ; Vol. 44, No. 10. pp. 445-447.
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