C1-C2 arthrodesis after spontaneous Propionibacterium acnes spondylodiscitis: Case report and literature analysis

Paolo Di Russo, Carlo Tascini, Maria Elena Benini, Carlotta Martini, Paolo Lepori

Research output: Contribution to journalArticle

Abstract

Background: Propionibacterium acnes (P. acnes) is a microaerophilic anaerobic Gram-positive rod responsible for acne vulgaris. Although it is often considered to be a skin contaminant, it may act as a virulent agent in implant-associated infections. Conversely, spontaneous infectious processes have been rarely described. Case Description: Here, we describe a 43-year-old female with C1-C2 spondylodiscitis attributed to P. acnes infection. Despite long-term antibiotic treatment, computed tomography demonstrated erosion of the C1 and C2 vertebral complex that later warranted a fusion. One year postoperatively, the patient was asymptomatic. Conclusions: Clinical knowledge of P. acnes virulence in spontaneous cervical spondylodiscitis allows early diagnosis, which is necessary to prevent or reduce complications such as cervical deformity with myelopathy or mediastinitis.

Original languageEnglish
Article number14
JournalSurgical Neurology International
Volume9
Issue number1
DOIs
Publication statusPublished - Jan 1 2018
Externally publishedYes

Fingerprint

Discitis
Propionibacterium acnes
Arthrodesis
Gram-Positive Rods
Mediastinitis
Spinal Cord Diseases
Acne Vulgaris
Infection
Virulence
Early Diagnosis
Tomography
Anti-Bacterial Agents
Skin
Therapeutics

Keywords

  • Atlantoaxial fusion
  • cervical spinal cord
  • Propionibacterium acnes
  • spondylodiscitis

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

C1-C2 arthrodesis after spontaneous Propionibacterium acnes spondylodiscitis : Case report and literature analysis. / Di Russo, Paolo; Tascini, Carlo; Benini, Maria Elena; Martini, Carlotta; Lepori, Paolo.

In: Surgical Neurology International, Vol. 9, No. 1, 14, 01.01.2018.

Research output: Contribution to journalArticle

Di Russo, Paolo ; Tascini, Carlo ; Benini, Maria Elena ; Martini, Carlotta ; Lepori, Paolo. / C1-C2 arthrodesis after spontaneous Propionibacterium acnes spondylodiscitis : Case report and literature analysis. In: Surgical Neurology International. 2018 ; Vol. 9, No. 1.
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