In PC12 cells, activation of B2 receptors by bradykinin promotes an elevation of cytosolic Ca2+ by two mechanisms: IP3 mediated release of Ca2+ from intracellular stores and stimulation of multiple Ca2+ influx pathways. Since these events can have different kinetics and spatial localizations they can induce diversified effects in different cell areas.
|Journal||Agents and Actions Supplements|
|Publication status||Published - 1992|
ASJC Scopus subject areas
- Pharmacology (medical)