[Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells

F. Grohovaz, D. Zacchetti, P. D'Andrea, P. Lorenzon, J. Meldolesi

Research output: Contribution to journalArticle

Abstract

In PC12 cells, activation of B2 receptors by bradykinin promotes an elevation of cytosolic Ca2+ by two mechanisms: IP3 mediated release of Ca2+ from intracellular stores and stimulation of multiple Ca2+ influx pathways. Since these events can have different kinetics and spatial localizations they can induce diversified effects in different cell areas.

Original languageEnglish
Pages (from-to)9-15
Number of pages7
JournalAgents and Actions
Volume38
Issue numberSUPPL. II
Publication statusPublished - 1992

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Bradykinin B2 Receptors
PC12 Cells
Chemical activation
Kinetics

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Toxicology

Cite this

Grohovaz, F., Zacchetti, D., D'Andrea, P., Lorenzon, P., & Meldolesi, J. (1992). [Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells. Agents and Actions, 38(SUPPL. II), 9-15.

[Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells. / Grohovaz, F.; Zacchetti, D.; D'Andrea, P.; Lorenzon, P.; Meldolesi, J.

In: Agents and Actions, Vol. 38, No. SUPPL. II, 1992, p. 9-15.

Research output: Contribution to journalArticle

Grohovaz, F, Zacchetti, D, D'Andrea, P, Lorenzon, P & Meldolesi, J 1992, '[Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells', Agents and Actions, vol. 38, no. SUPPL. II, pp. 9-15.
Grohovaz, F. ; Zacchetti, D. ; D'Andrea, P. ; Lorenzon, P. ; Meldolesi, J. / [Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells. In: Agents and Actions. 1992 ; Vol. 38, No. SUPPL. II. pp. 9-15.
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