[Ca2+](i) effects of bradykinin B2 receptor activation in PC12 cells

F. Grohovaz, D. Zacchetti, P. D'Andrea, P. Lorenzon, J. Meldolesi

Research output: Contribution to journalArticlepeer-review


In PC12 cells, activation of B2 receptors by bradykinin promotes an elevation of cytosolic Ca2+ by two mechanisms: IP3 mediated release of Ca2+ from intracellular stores and stimulation of multiple Ca2+ influx pathways. Since these events can have different kinetics and spatial localizations they can induce diversified effects in different cell areas.

Original languageEnglish
Pages (from-to)9-15
Number of pages7
JournalAgents and Actions
Issue numberSUPPL. II
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Toxicology


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