Calcium and sodium transport in gestational hypertension

Andrea Luigi Tranquilli, Rosa Anna Rabini, Anna Maria Cugini, Nelvio Cester, Herbert Valensise, Carlo Romanini, Enrico Bertoli, Laura Mazzanti

Research output: Contribution to journalArticlepeer-review


The enzymatic activities of Na+/K+ ATPase and Ca2+ ATPase were determined on erythrocyte membranes from 9 normotensive and 9 gestational hypertensive pregnant women near term. A reduction in the activity of the Na+/K+ ATPase and a relative increase in the activity of the Ca2+ ATPase were found in the hypertensive patients, possibly due to a conformational alteration of erythrocyte membranes. This observation supports the possible role of the transmembrane cation transport in the pathogenesis of gestational hypertension.

Original languageEnglish
JournalInternational Journal of Cardiology
Issue numberSUPPL. 1
Publication statusPublished - 1989


  • Cation transport
  • Hypertension
  • Pregnancy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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