Calcium entry blocker: Treatment in acute pain in cluster headache patients

A. Boiardi; M. Gemma; E. Porta; C. Peccarisi; G. Bussone

doi:10.1007/BF02342033

Calcium entry blocker: Treatment in acute pain in cluster headache patients

A. Boiardi, M. Gemma, E. Porta, C. Peccarisi, G. Bussone

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

15 chronic cluster headache patients in whom pain was induced by nitroglycerin received acute intravenous treatment with a calcium entry blocker. At the time of peak pain we noted a sudden decrease after the Verapamil injection. The mechanism by which the calcium entry blocker afforded relief is unlikely to have been vasodilatation in patients whose blood vessels had just been dilated by nitroglycerin. A more probable mechanism is blockade of the release of the pain-inducing neurotransmitters. The vasodilatation phase is not a primary factor in the onset of pain.

Original language	English
Pages (from-to)	531-534
Number of pages	4
Journal	Italian Journal of Neurological Sciences
Volume	7
Issue number	5
DOIs	https://doi.org/10.1007/BF02342033
Publication status	Published - Oct 1986

Keywords

acute treatment
Calcium entry blocker
cluster headache

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

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abstract = "15 chronic cluster headache patients in whom pain was induced by nitroglycerin received acute intravenous treatment with a calcium entry blocker. At the time of peak pain we noted a sudden decrease after the Verapamil injection. The mechanism by which the calcium entry blocker afforded relief is unlikely to have been vasodilatation in patients whose blood vessels had just been dilated by nitroglycerin. A more probable mechanism is blockade of the release of the pain-inducing neurotransmitters. The vasodilatation phase is not a primary factor in the onset of pain.",

keywords = "acute treatment, Calcium entry blocker, cluster headache",

author = "A. Boiardi and M. Gemma and E. Porta and C. Peccarisi and G. Bussone",

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T2 - Treatment in acute pain in cluster headache patients

AU - Boiardi, A.

AU - Gemma, M.

AU - Porta, E.

AU - Peccarisi, C.

AU - Bussone, G.

PY - 1986/10

Y1 - 1986/10

N2 - 15 chronic cluster headache patients in whom pain was induced by nitroglycerin received acute intravenous treatment with a calcium entry blocker. At the time of peak pain we noted a sudden decrease after the Verapamil injection. The mechanism by which the calcium entry blocker afforded relief is unlikely to have been vasodilatation in patients whose blood vessels had just been dilated by nitroglycerin. A more probable mechanism is blockade of the release of the pain-inducing neurotransmitters. The vasodilatation phase is not a primary factor in the onset of pain.

AB - 15 chronic cluster headache patients in whom pain was induced by nitroglycerin received acute intravenous treatment with a calcium entry blocker. At the time of peak pain we noted a sudden decrease after the Verapamil injection. The mechanism by which the calcium entry blocker afforded relief is unlikely to have been vasodilatation in patients whose blood vessels had just been dilated by nitroglycerin. A more probable mechanism is blockade of the release of the pain-inducing neurotransmitters. The vasodilatation phase is not a primary factor in the onset of pain.

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KW - Calcium entry blocker

KW - cluster headache

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JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 5

ER -

Calcium entry blocker: Treatment in acute pain in cluster headache patients

Abstract

Keywords

ASJC Scopus subject areas

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