Campylobacter jejuni bacteremia and Guillain-Barre syndrome in a renal transplant recipient

Massimo Maccario, Antonio Tarantino, Eduardo Nobile-Orazio, Claudio Ponticelli

Research output: Contribution to journalArticle

Abstract

In patients who have not undergone transplantation, Guillain-Barre syndrome (GBS) is typically preceded by an acute infection often sustained by Campylobacter jejuni. Thus far, in renal transplant recipients, only eight cases of GBS have been reported. In seven patients GBS was attributed to cytomegalovirus infection and in the eighth patient to cyclosporin A neurotoxicity. We report here the case of a GBS in a renal transplant recipient following C. jejuni bacteremia. The infection quickly disappeared after erythromycin and methronidazole therapy. GBS progressively evolved into a paraparesis within 1 week. After reaching a plateau phase, the clinical status improved and the patient was able to walk unassisted after 3 weeks. At his last check-up, 54 months later, the patient was doing well with a functioning graft and only minimal weakness of the lower limbs.

Original languageEnglish
Pages (from-to)439-442
Number of pages4
JournalTransplant International
Volume11
Issue number6
DOIs
Publication statusPublished - Nov 1998

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Keywords

  • Campylobacter jejuni, Guillain-Barre syndrome, renal transplantation
  • Guillain-Barre syndrome, Campylobacter jejuni, renal transplantation
  • Renal transplantation, Campylobacter jejuni, Guillain-Barre syndrome

ASJC Scopus subject areas

  • Transplantation

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