Can a very-low-fat diet achieve cholesterol goals in CAD?

R. Aquilani, R. Tramarin, R. F E Pedretti, G. Bertolotti, M. Sommaruga, P. Mariani, L. Ruffato, M. Catapano, F. Boschi, M. Dossena, O. Pastoris

Research output: Contribution to journalArticlepeer-review


We enrolled 126 male nonsmoking coronary artery disease (CAD) outpatients to determine if a very-low-fat diet with or without an accompanying 10-mg daily dose of simvastatin could achieve a low-density lipoprotein (LDL) cholesterol level of 2.5 mmol/L or lower. Compliance was ensured with a highly simplified diet regimen. No patients reduced LDL to the target value with diet alone, whereas 33% achieved the goal with diet plus drug. Thus, diet alone, even when based on restricted lipid content and a simplified regimen, cannot achieve cholesterol goals in CAD.

Original languageEnglish
Pages (from-to)36-40
Number of pages5
JournalCardiology Review
Issue number10
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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