Cancer Burden in Adolescents and Young Adults

A Review of Epidemiological Evidence

Annalisa Trama, Laura Botta, Eva Steliarova-Foucher

Research output: Contribution to journalArticle

Abstract

Cancer burden in adolescents and young adults (AYAs) is expressed through a large proportion of the quality of life lost on individual level and also causes losses to the society in terms of a decreased productivity and social structure. A specific cancer spectrum and distinctive needs of AYA patients require targeted studies and cancer control measures. Incidence is intermediate between that for children and for older adults, and two-thirds of the AYA cancers affect women. Cancers of the breast and cervix uteri, representing a large portion of the burden, are amenable to prevention. Survival is relatively high, but it is lower in AYA patients with certain cancers that are common in childhood or older adulthood. Tailored cancer care with centralized multidisciplinary provision improves the outcome, as demonstrated by survival of leukemia patients. Mortality is decreasing in high-income countries for the cancers that contribute to the burden most, but lack of progress is seen for some rarer subtypes, such as brain tumors and sarcomas of the bone and soft tissue. There is unacceptable lack of information on cancer burden in low-income countries in which the outcomes for AYA patients are likely dreadful. Investment is required to establish cancer registration system and appropriate cancer care delivery in these settings.

Original languageEnglish
Pages (from-to)256-266
Number of pages11
JournalCancer Journal
Volume24
Issue number6
DOIs
Publication statusPublished - Nov 28 2018

Fingerprint

Young Adult
Neoplasms
Uterine Neoplasms
Survival
Cervix Uteri
Brain Neoplasms
Uterine Cervical Neoplasms
Sarcoma
Leukemia
Quality of Life
Breast Neoplasms
Bone and Bones
Mortality
Incidence

Cite this

Cancer Burden in Adolescents and Young Adults : A Review of Epidemiological Evidence. / Trama, Annalisa; Botta, Laura; Steliarova-Foucher, Eva.

In: Cancer Journal, Vol. 24, No. 6, 28.11.2018, p. 256-266.

Research output: Contribution to journalArticle

Trama, Annalisa ; Botta, Laura ; Steliarova-Foucher, Eva. / Cancer Burden in Adolescents and Young Adults : A Review of Epidemiological Evidence. In: Cancer Journal. 2018 ; Vol. 24, No. 6. pp. 256-266.
@article{8addf7dc0be24972a0d424fd49b4b2d7,
title = "Cancer Burden in Adolescents and Young Adults: A Review of Epidemiological Evidence",
abstract = "Cancer burden in adolescents and young adults (AYAs) is expressed through a large proportion of the quality of life lost on individual level and also causes losses to the society in terms of a decreased productivity and social structure. A specific cancer spectrum and distinctive needs of AYA patients require targeted studies and cancer control measures. Incidence is intermediate between that for children and for older adults, and two-thirds of the AYA cancers affect women. Cancers of the breast and cervix uteri, representing a large portion of the burden, are amenable to prevention. Survival is relatively high, but it is lower in AYA patients with certain cancers that are common in childhood or older adulthood. Tailored cancer care with centralized multidisciplinary provision improves the outcome, as demonstrated by survival of leukemia patients. Mortality is decreasing in high-income countries for the cancers that contribute to the burden most, but lack of progress is seen for some rarer subtypes, such as brain tumors and sarcomas of the bone and soft tissue. There is unacceptable lack of information on cancer burden in low-income countries in which the outcomes for AYA patients are likely dreadful. Investment is required to establish cancer registration system and appropriate cancer care delivery in these settings.",
author = "Annalisa Trama and Laura Botta and Eva Steliarova-Foucher",
year = "2018",
month = "11",
day = "28",
doi = "10.1097/PPO.0000000000000346",
language = "English",
volume = "24",
pages = "256--266",
journal = "Cancer journal (Sudbury, Mass.)",
issn = "0765-7846",
publisher = "Association Pour le Developpement de la Communication Cancerologique",
number = "6",

}

TY - JOUR

T1 - Cancer Burden in Adolescents and Young Adults

T2 - A Review of Epidemiological Evidence

AU - Trama, Annalisa

AU - Botta, Laura

AU - Steliarova-Foucher, Eva

PY - 2018/11/28

Y1 - 2018/11/28

N2 - Cancer burden in adolescents and young adults (AYAs) is expressed through a large proportion of the quality of life lost on individual level and also causes losses to the society in terms of a decreased productivity and social structure. A specific cancer spectrum and distinctive needs of AYA patients require targeted studies and cancer control measures. Incidence is intermediate between that for children and for older adults, and two-thirds of the AYA cancers affect women. Cancers of the breast and cervix uteri, representing a large portion of the burden, are amenable to prevention. Survival is relatively high, but it is lower in AYA patients with certain cancers that are common in childhood or older adulthood. Tailored cancer care with centralized multidisciplinary provision improves the outcome, as demonstrated by survival of leukemia patients. Mortality is decreasing in high-income countries for the cancers that contribute to the burden most, but lack of progress is seen for some rarer subtypes, such as brain tumors and sarcomas of the bone and soft tissue. There is unacceptable lack of information on cancer burden in low-income countries in which the outcomes for AYA patients are likely dreadful. Investment is required to establish cancer registration system and appropriate cancer care delivery in these settings.

AB - Cancer burden in adolescents and young adults (AYAs) is expressed through a large proportion of the quality of life lost on individual level and also causes losses to the society in terms of a decreased productivity and social structure. A specific cancer spectrum and distinctive needs of AYA patients require targeted studies and cancer control measures. Incidence is intermediate between that for children and for older adults, and two-thirds of the AYA cancers affect women. Cancers of the breast and cervix uteri, representing a large portion of the burden, are amenable to prevention. Survival is relatively high, but it is lower in AYA patients with certain cancers that are common in childhood or older adulthood. Tailored cancer care with centralized multidisciplinary provision improves the outcome, as demonstrated by survival of leukemia patients. Mortality is decreasing in high-income countries for the cancers that contribute to the burden most, but lack of progress is seen for some rarer subtypes, such as brain tumors and sarcomas of the bone and soft tissue. There is unacceptable lack of information on cancer burden in low-income countries in which the outcomes for AYA patients are likely dreadful. Investment is required to establish cancer registration system and appropriate cancer care delivery in these settings.

U2 - 10.1097/PPO.0000000000000346

DO - 10.1097/PPO.0000000000000346

M3 - Article

VL - 24

SP - 256

EP - 266

JO - Cancer journal (Sudbury, Mass.)

JF - Cancer journal (Sudbury, Mass.)

SN - 0765-7846

IS - 6

ER -