Abstract
The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
| Original language | English |
|---|---|
| Publisher | Springer Netherlands |
| Number of pages | 588 |
| ISBN (Print) | 9789400758421, 9400758413, 9789400758414 |
| DOIs | |
| Publication status | Published - Sep 1 2013 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Cancer genomics : Molecular classification, prognosis and response prediction. / Pfeffer, Ulrich.
Springer Netherlands, 2013. 588 p.Research output: Book/Report › Book
}
TY - BOOK
T1 - Cancer genomics
T2 - Molecular classification, prognosis and response prediction
AU - Pfeffer, Ulrich
PY - 2013/9/1
Y1 - 2013/9/1
N2 - The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
AB - The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
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UR - http://www.scopus.com/inward/citedby.url?scp=84932631654&partnerID=8YFLogxK
U2 - 10.1007/978-94-007-5842-1
DO - 10.1007/978-94-007-5842-1
M3 - Book
AN - SCOPUS:84932631654
SN - 9789400758421
SN - 9400758413
SN - 9789400758414
BT - Cancer genomics
PB - Springer Netherlands
ER -