TY - JOUR
T1 - Cancer in pregnancy
T2 - Proposal of an italian multicenter study. gynecologic oncology group of the italian society of gynecology and obstetrics (sigo)
AU - Italian Society of Gynecology Obstetrics (SIGO)
AU - Sartori, Enrico
AU - Franchi, Massimo
AU - Capelli, Giovanni
AU - Cicinelli, Ettore
AU - Colacurci, Nicola
AU - De Vincenzo, Rosa
AU - Landoni, Fabio
AU - Maggino, Tiziano
AU - Masturzo, Bianca
AU - Parazzini, Fabio
AU - Scarfone, Giovanna
AU - Peccatori, Fedro
AU - Romagnolo, Cesare
AU - Scibilia, Giuseppe
AU - Scollo, Paolo
AU - Zola, Paolo
AU - Garzon, Simone
AU - Raffaelli, Ricciarda
AU - Busato, Enrico
AU - Cetin, Irene
AU - Giovannini, Massimo
AU - Zanni, Giuliano Carlo
AU - Greggi, Stefano
AU - Marconi, Anna Maria
AU - Rizzo, Nicola
AU - Ruspa, Giovanni
AU - Meroni, Mario Giuseppe
AU - Volpi, Eugenio Oreste
AU - Simoncini, Tommaso
AU - Gadducci, Angiolo
AU - Ghezzi, Fabio
AU - Laganà, Antonio Simone
AU - Melis, Gian Benedetto
AU - Paoletti, Anna Maria
AU - Strobelt, Nicola
AU - Spinillo, Arsenio
AU - Severi, Filiberto Maria
AU - Frusca, Tiziana
AU - Greco, Pantaleo
AU - Nappi, Luigi
AU - Ricci, Giuseppe
AU - Vizza, Enrico
AU - Papaccio, Marta
AU - Ratti, Martina
AU - Scambia, Giovanni
PY - 2018/1/1
Y1 - 2018/1/1
N2 - A pregnancy related cancer is defined as a neoplasm diagnosed in a woman during gestation or within 12 months following childbirth or abortion. Breast, thyroidal, melanoma, cervical and hematological malignancies are those most commonly diagnosed during pregnancy, with a reported incidence considered lower than those estimated of 1 case on 1000 pregnancies. The clinical complexity is generated by the co-presence of mother and fetus, and the consequent conflict represented by the need to identify a therapeutic strategy that is effective for the maternal prognosis and, at the same time, safeguards the fetal well-being. Moreover, the counseling, diagnosis, staging and management of these cases are further complicated because most of the scientific literature consists in case reports or small retrospective studies and lacks in guidelines and prospective clinical trials. On that basis, the Study Group on Cancer in Pregnancy (members of S.I.G.O.-Italian Society of Gynecology and Obstetrics) presents the TIGRE Trial, an Italian multicenter observational study aimed at establishing a shared database for the collection of epidemiological and clinical data of the patients affected by pregnancy related cancer in Italy, with the final objective to improve the outcome of a mother and a child involved in a such pathology.
AB - A pregnancy related cancer is defined as a neoplasm diagnosed in a woman during gestation or within 12 months following childbirth or abortion. Breast, thyroidal, melanoma, cervical and hematological malignancies are those most commonly diagnosed during pregnancy, with a reported incidence considered lower than those estimated of 1 case on 1000 pregnancies. The clinical complexity is generated by the co-presence of mother and fetus, and the consequent conflict represented by the need to identify a therapeutic strategy that is effective for the maternal prognosis and, at the same time, safeguards the fetal well-being. Moreover, the counseling, diagnosis, staging and management of these cases are further complicated because most of the scientific literature consists in case reports or small retrospective studies and lacks in guidelines and prospective clinical trials. On that basis, the Study Group on Cancer in Pregnancy (members of S.I.G.O.-Italian Society of Gynecology and Obstetrics) presents the TIGRE Trial, an Italian multicenter observational study aimed at establishing a shared database for the collection of epidemiological and clinical data of the patients affected by pregnancy related cancer in Italy, with the final objective to improve the outcome of a mother and a child involved in a such pathology.
KW - Chemotherapy
KW - Fetal development
KW - Multicenter observational study
KW - Pregnancy related cancer
KW - Teratogenic risk
KW - Tiger trial
UR - http://www.scopus.com/inward/record.url?scp=85055049471&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055049471&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85055049471
VL - 30
SP - 37
EP - 44
JO - Italian Journal of Gynaecology and Obstetrics
JF - Italian Journal of Gynaecology and Obstetrics
SN - 1121-8339
IS - 3
ER -