Cancer mortality by urbanization and proximity to the sea coast in Campania region, southern Italy

Ettore Bidoli, Silvia Franceschi, Maurizio Montella

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Aims and background: The risk for several cancers is higher in urban than in rural areas. The gradient has seldom been studied in southern Europe. Patients and methods: The geographical pattern of mortality for different cancers and all causes was studied in the Campania Region (about 5.6 million inhabitants), whose largest town is Naples. The key variables were residence in urban/rural and coastal/inland municipalities. Relative risks of death and corresponding 95% confidence intervals by residence were evaluated by means of Poisson loglinear regression models. Results: Significantly increased mortality rates in urban compared to rural municipalities were found for several cancer causes of death. In particular, in both sexes, excesses in the order of 30-50% were observed for tobacco-related neoplasms (i.e., larynx, lung, and bladder) and cancers of the intestine, liver, brain, multiple myeloma and non-Hodgkin's lymphoma, in addition to all-cancer, and all-cause mortality. In females, specific excesses were also noticed for cancer of the gallbladder, pancreas, breast and uterus (corpus and cervix). Conversely, significantly decreased mortality rates in urban with respect to rural municipalities were observed for cancer of the oral cavity and pharynx in males. Coastal location and degree of urbanization were strongly correlated, thus showing similar associations with most causes of death. However, a significant excess of cancer of the pleura in males was restricted to coastal municipalities. Conclusions: Anti-smoking campaigns, sanitation improvements, hepatitis B vaccination, and a decrease in obesity emerge as high priorities with respect to cancer control strategies in the Campania Region, particularly in overpopulated, underprivileged urban areas.

Original languageEnglish
Pages (from-to)460-466
Number of pages7
JournalTumori
Volume84
Issue number4
Publication statusPublished - Jul 1998

Fingerprint

Urbanization
Oceans and Seas
Italy
Mortality
Neoplasms
Cause of Death
Pharyngeal Neoplasms
Intestinal Neoplasms
Gallbladder Neoplasms
Uterine Neoplasms
Sanitation
Laryngeal Neoplasms
Pleura
Mouth Neoplasms
Liver Neoplasms
Hepatitis B
Multiple Myeloma
Pancreatic Neoplasms
Urinary Bladder Neoplasms
Cervix Uteri

Keywords

  • Cancer
  • Mortality
  • Urban/rural gradient

ASJC Scopus subject areas

  • Cancer Research

Cite this

Cancer mortality by urbanization and proximity to the sea coast in Campania region, southern Italy. / Bidoli, Ettore; Franceschi, Silvia; Montella, Maurizio.

In: Tumori, Vol. 84, No. 4, 07.1998, p. 460-466.

Research output: Contribution to journalArticle

@article{0cf81e5b4ff347c1bf73634f17ec6dc4,
title = "Cancer mortality by urbanization and proximity to the sea coast in Campania region, southern Italy",
abstract = "Aims and background: The risk for several cancers is higher in urban than in rural areas. The gradient has seldom been studied in southern Europe. Patients and methods: The geographical pattern of mortality for different cancers and all causes was studied in the Campania Region (about 5.6 million inhabitants), whose largest town is Naples. The key variables were residence in urban/rural and coastal/inland municipalities. Relative risks of death and corresponding 95{\%} confidence intervals by residence were evaluated by means of Poisson loglinear regression models. Results: Significantly increased mortality rates in urban compared to rural municipalities were found for several cancer causes of death. In particular, in both sexes, excesses in the order of 30-50{\%} were observed for tobacco-related neoplasms (i.e., larynx, lung, and bladder) and cancers of the intestine, liver, brain, multiple myeloma and non-Hodgkin's lymphoma, in addition to all-cancer, and all-cause mortality. In females, specific excesses were also noticed for cancer of the gallbladder, pancreas, breast and uterus (corpus and cervix). Conversely, significantly decreased mortality rates in urban with respect to rural municipalities were observed for cancer of the oral cavity and pharynx in males. Coastal location and degree of urbanization were strongly correlated, thus showing similar associations with most causes of death. However, a significant excess of cancer of the pleura in males was restricted to coastal municipalities. Conclusions: Anti-smoking campaigns, sanitation improvements, hepatitis B vaccination, and a decrease in obesity emerge as high priorities with respect to cancer control strategies in the Campania Region, particularly in overpopulated, underprivileged urban areas.",
keywords = "Cancer, Mortality, Urban/rural gradient",
author = "Ettore Bidoli and Silvia Franceschi and Maurizio Montella",
year = "1998",
month = "7",
language = "English",
volume = "84",
pages = "460--466",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "4",

}

TY - JOUR

T1 - Cancer mortality by urbanization and proximity to the sea coast in Campania region, southern Italy

AU - Bidoli, Ettore

AU - Franceschi, Silvia

AU - Montella, Maurizio

PY - 1998/7

Y1 - 1998/7

N2 - Aims and background: The risk for several cancers is higher in urban than in rural areas. The gradient has seldom been studied in southern Europe. Patients and methods: The geographical pattern of mortality for different cancers and all causes was studied in the Campania Region (about 5.6 million inhabitants), whose largest town is Naples. The key variables were residence in urban/rural and coastal/inland municipalities. Relative risks of death and corresponding 95% confidence intervals by residence were evaluated by means of Poisson loglinear regression models. Results: Significantly increased mortality rates in urban compared to rural municipalities were found for several cancer causes of death. In particular, in both sexes, excesses in the order of 30-50% were observed for tobacco-related neoplasms (i.e., larynx, lung, and bladder) and cancers of the intestine, liver, brain, multiple myeloma and non-Hodgkin's lymphoma, in addition to all-cancer, and all-cause mortality. In females, specific excesses were also noticed for cancer of the gallbladder, pancreas, breast and uterus (corpus and cervix). Conversely, significantly decreased mortality rates in urban with respect to rural municipalities were observed for cancer of the oral cavity and pharynx in males. Coastal location and degree of urbanization were strongly correlated, thus showing similar associations with most causes of death. However, a significant excess of cancer of the pleura in males was restricted to coastal municipalities. Conclusions: Anti-smoking campaigns, sanitation improvements, hepatitis B vaccination, and a decrease in obesity emerge as high priorities with respect to cancer control strategies in the Campania Region, particularly in overpopulated, underprivileged urban areas.

AB - Aims and background: The risk for several cancers is higher in urban than in rural areas. The gradient has seldom been studied in southern Europe. Patients and methods: The geographical pattern of mortality for different cancers and all causes was studied in the Campania Region (about 5.6 million inhabitants), whose largest town is Naples. The key variables were residence in urban/rural and coastal/inland municipalities. Relative risks of death and corresponding 95% confidence intervals by residence were evaluated by means of Poisson loglinear regression models. Results: Significantly increased mortality rates in urban compared to rural municipalities were found for several cancer causes of death. In particular, in both sexes, excesses in the order of 30-50% were observed for tobacco-related neoplasms (i.e., larynx, lung, and bladder) and cancers of the intestine, liver, brain, multiple myeloma and non-Hodgkin's lymphoma, in addition to all-cancer, and all-cause mortality. In females, specific excesses were also noticed for cancer of the gallbladder, pancreas, breast and uterus (corpus and cervix). Conversely, significantly decreased mortality rates in urban with respect to rural municipalities were observed for cancer of the oral cavity and pharynx in males. Coastal location and degree of urbanization were strongly correlated, thus showing similar associations with most causes of death. However, a significant excess of cancer of the pleura in males was restricted to coastal municipalities. Conclusions: Anti-smoking campaigns, sanitation improvements, hepatitis B vaccination, and a decrease in obesity emerge as high priorities with respect to cancer control strategies in the Campania Region, particularly in overpopulated, underprivileged urban areas.

KW - Cancer

KW - Mortality

KW - Urban/rural gradient

UR - http://www.scopus.com/inward/record.url?scp=0031725917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031725917&partnerID=8YFLogxK

M3 - Article

C2 - 9824997

AN - SCOPUS:0031725917

VL - 84

SP - 460

EP - 466

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 4

ER -