Cancer mortality trend analysis in Italy, 1970-2007

Andrea Arfè, Matteo Malvezzi, Paola Bertuccio, Adriano Decarli, Carlo La Vecchia, Eva Negri

Research output: Contribution to journalArticle

Abstract

To provide an updated review of cancer mortality trends in Italy, cancer mortality and census data, from 1970 to 2007, were extracted from the WHO mortality database and analyzed using age-specific and standardized rates, and joinpoint regression. Total cancer mortality rates in men have been declining by 1.8% yearly since 1994, reaching a rate of 147 per 100 000 residents (world standard) in 2007. In women, total cancer mortality rates have been decreasing by 1.1% yearly since 1991, resulting in a standardized mortality rate of 85 per 100 000 residents in 2007. Avoided deaths, compared with rates of 1988, from lung, intestinal, stomach, and breast cancers amount to 30 646. In men, trends were driven by cancers of the lung and other tobacco-related sites, intestines, and stomach. Favorable trends for cancers of the breast, intestines, stomach, and uterus contributed to falls in mortality rate in women. Downward trends were seen in both sexes for Hodgkin's lymphoma, bone cancer, and leukemias. Lung cancer in women showed an upward trend, with mortality rates increasing by 2.6% yearly since 1997, becoming the second cause of cancer mortality in middle-aged women. Rising trends were seen in women for oral and pancreatic cancers, as well. The favorable trends in cancer mortality are related to reduced tobacco smoking and alcohol consumption in men, advancements in treatment and management for colorectal cancer, breast cancer, leukemias, and a few other rare treatable cancers, and improved diagnosis of colorectal, breast, and cervical cancers. The greater role of tobacco-related deaths in women suggests the need for targeted strategies.

Original languageEnglish
Pages (from-to)364-374
Number of pages11
JournalEuropean Journal of Cancer Prevention
Volume20
Issue number5
DOIs
Publication statusPublished - Sep 2011

Fingerprint

Italy
Mortality
Neoplasms
Breast Neoplasms
Intestinal Neoplasms
Lung Neoplasms
Tobacco
Colorectal Neoplasms
Stomach
Leukemia
Bone Neoplasms
Second Primary Neoplasms
Mouth Neoplasms
Tobacco Use
Censuses
Hodgkin Disease
Pancreatic Neoplasms
Uterine Cervical Neoplasms
Alcohol Drinking
Stomach Neoplasms

Keywords

  • cancer
  • epidemiology
  • Italy
  • mortality
  • trends

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Arfè, A., Malvezzi, M., Bertuccio, P., Decarli, A., La Vecchia, C., & Negri, E. (2011). Cancer mortality trend analysis in Italy, 1970-2007. European Journal of Cancer Prevention, 20(5), 364-374. https://doi.org/10.1097/CEJ.0b013e328345f99e

Cancer mortality trend analysis in Italy, 1970-2007. / Arfè, Andrea; Malvezzi, Matteo; Bertuccio, Paola; Decarli, Adriano; La Vecchia, Carlo; Negri, Eva.

In: European Journal of Cancer Prevention, Vol. 20, No. 5, 09.2011, p. 364-374.

Research output: Contribution to journalArticle

Arfè, A, Malvezzi, M, Bertuccio, P, Decarli, A, La Vecchia, C & Negri, E 2011, 'Cancer mortality trend analysis in Italy, 1970-2007', European Journal of Cancer Prevention, vol. 20, no. 5, pp. 364-374. https://doi.org/10.1097/CEJ.0b013e328345f99e
Arfè A, Malvezzi M, Bertuccio P, Decarli A, La Vecchia C, Negri E. Cancer mortality trend analysis in Italy, 1970-2007. European Journal of Cancer Prevention. 2011 Sep;20(5):364-374. https://doi.org/10.1097/CEJ.0b013e328345f99e
Arfè, Andrea ; Malvezzi, Matteo ; Bertuccio, Paola ; Decarli, Adriano ; La Vecchia, Carlo ; Negri, Eva. / Cancer mortality trend analysis in Italy, 1970-2007. In: European Journal of Cancer Prevention. 2011 ; Vol. 20, No. 5. pp. 364-374.
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