Cancer risk in waterpipe smokers

a meta-analysis

Ravinder Mamtani, Sohaila Cheema, Javaid Sheikh, Ahmad Al Mulla, Albert Lowenfels, Patrick Maisonneuve

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

OBJECTIVES: To quantify by meta-analysis the relationship between waterpipe smoking and cancer, including cancer of the head and neck, esophagus, stomach, lung and bladder.

METHODS: We performed a systematic literature search to identify relevant studies, scored their quality, used fixed and random-effect models to estimate summary relative risks (SRR), evaluated heterogeneity and publication bias.

RESULTS: We retrieved information from 28 published reports. Considering only highquality studies, waterpipe smoking was associated with increased risk of head and neck cancer (SRR 2.97; 95 % CI 2.26-3.90), esophageal cancer (1.84; 1.42-2.38) and lung cancer (2.22; 1.24-3.97), with no evidence of heterogeneity or publication bias. Increased risk was also observed for stomach and bladder cancer but based mainly on poor-quality studies. For colorectum, liver and for all sites combined risk estimates were elevated, but there were insufficient reports to perform a meta-analysis.

CONCLUSIONS: Contrary to the perception of the relative safety of waterpipe smoking, this meta-analysis provides quantitative estimates of its association with cancers of the head and neck, esophagus and lung. The scarcity and limited quality of available reports point out the need for larger carefully designed studies in well-defined populations.

Original languageEnglish
Pages (from-to)73-83
Number of pages11
JournalSozial- und Praventivmedizin
Volume62
Issue number1
DOIs
Publication statusPublished - Jan 2017

Fingerprint

Meta-Analysis
Head and Neck Neoplasms
Publication Bias
Smoking
Neoplasms
Esophagus
Lung Neoplasms
Esophageal Neoplasms
Urinary Bladder Neoplasms
Stomach Neoplasms
Stomach
Urinary Bladder
Safety
Lung
Liver
Population

Keywords

  • Humans
  • Neoplasms/etiology
  • Risk
  • Smoking/adverse effects
  • Tobacco Products/adverse effects
  • Water

Cite this

Cancer risk in waterpipe smokers : a meta-analysis. / Mamtani, Ravinder; Cheema, Sohaila; Sheikh, Javaid; Al Mulla, Ahmad; Lowenfels, Albert; Maisonneuve, Patrick.

In: Sozial- und Praventivmedizin, Vol. 62, No. 1, 01.2017, p. 73-83.

Research output: Contribution to journalArticle

Mamtani, R, Cheema, S, Sheikh, J, Al Mulla, A, Lowenfels, A & Maisonneuve, P 2017, 'Cancer risk in waterpipe smokers: a meta-analysis', Sozial- und Praventivmedizin, vol. 62, no. 1, pp. 73-83. https://doi.org/10.1007/s00038-016-0856-2
Mamtani, Ravinder ; Cheema, Sohaila ; Sheikh, Javaid ; Al Mulla, Ahmad ; Lowenfels, Albert ; Maisonneuve, Patrick. / Cancer risk in waterpipe smokers : a meta-analysis. In: Sozial- und Praventivmedizin. 2017 ; Vol. 62, No. 1. pp. 73-83.
@article{599f89ac625345c7ba83d5a167359f94,
title = "Cancer risk in waterpipe smokers: a meta-analysis",
abstract = "OBJECTIVES: To quantify by meta-analysis the relationship between waterpipe smoking and cancer, including cancer of the head and neck, esophagus, stomach, lung and bladder.METHODS: We performed a systematic literature search to identify relevant studies, scored their quality, used fixed and random-effect models to estimate summary relative risks (SRR), evaluated heterogeneity and publication bias.RESULTS: We retrieved information from 28 published reports. Considering only highquality studies, waterpipe smoking was associated with increased risk of head and neck cancer (SRR 2.97; 95 {\%} CI 2.26-3.90), esophageal cancer (1.84; 1.42-2.38) and lung cancer (2.22; 1.24-3.97), with no evidence of heterogeneity or publication bias. Increased risk was also observed for stomach and bladder cancer but based mainly on poor-quality studies. For colorectum, liver and for all sites combined risk estimates were elevated, but there were insufficient reports to perform a meta-analysis.CONCLUSIONS: Contrary to the perception of the relative safety of waterpipe smoking, this meta-analysis provides quantitative estimates of its association with cancers of the head and neck, esophagus and lung. The scarcity and limited quality of available reports point out the need for larger carefully designed studies in well-defined populations.",
keywords = "Humans, Neoplasms/etiology, Risk, Smoking/adverse effects, Tobacco Products/adverse effects, Water",
author = "Ravinder Mamtani and Sohaila Cheema and Javaid Sheikh and {Al Mulla}, Ahmad and Albert Lowenfels and Patrick Maisonneuve",
year = "2017",
month = "1",
doi = "10.1007/s00038-016-0856-2",
language = "English",
volume = "62",
pages = "73--83",
journal = "Sozial- und Praventivmedizin",
issn = "1661-8556",
publisher = "Birkhauser Verlag Basel",
number = "1",

}

TY - JOUR

T1 - Cancer risk in waterpipe smokers

T2 - a meta-analysis

AU - Mamtani, Ravinder

AU - Cheema, Sohaila

AU - Sheikh, Javaid

AU - Al Mulla, Ahmad

AU - Lowenfels, Albert

AU - Maisonneuve, Patrick

PY - 2017/1

Y1 - 2017/1

N2 - OBJECTIVES: To quantify by meta-analysis the relationship between waterpipe smoking and cancer, including cancer of the head and neck, esophagus, stomach, lung and bladder.METHODS: We performed a systematic literature search to identify relevant studies, scored their quality, used fixed and random-effect models to estimate summary relative risks (SRR), evaluated heterogeneity and publication bias.RESULTS: We retrieved information from 28 published reports. Considering only highquality studies, waterpipe smoking was associated with increased risk of head and neck cancer (SRR 2.97; 95 % CI 2.26-3.90), esophageal cancer (1.84; 1.42-2.38) and lung cancer (2.22; 1.24-3.97), with no evidence of heterogeneity or publication bias. Increased risk was also observed for stomach and bladder cancer but based mainly on poor-quality studies. For colorectum, liver and for all sites combined risk estimates were elevated, but there were insufficient reports to perform a meta-analysis.CONCLUSIONS: Contrary to the perception of the relative safety of waterpipe smoking, this meta-analysis provides quantitative estimates of its association with cancers of the head and neck, esophagus and lung. The scarcity and limited quality of available reports point out the need for larger carefully designed studies in well-defined populations.

AB - OBJECTIVES: To quantify by meta-analysis the relationship between waterpipe smoking and cancer, including cancer of the head and neck, esophagus, stomach, lung and bladder.METHODS: We performed a systematic literature search to identify relevant studies, scored their quality, used fixed and random-effect models to estimate summary relative risks (SRR), evaluated heterogeneity and publication bias.RESULTS: We retrieved information from 28 published reports. Considering only highquality studies, waterpipe smoking was associated with increased risk of head and neck cancer (SRR 2.97; 95 % CI 2.26-3.90), esophageal cancer (1.84; 1.42-2.38) and lung cancer (2.22; 1.24-3.97), with no evidence of heterogeneity or publication bias. Increased risk was also observed for stomach and bladder cancer but based mainly on poor-quality studies. For colorectum, liver and for all sites combined risk estimates were elevated, but there were insufficient reports to perform a meta-analysis.CONCLUSIONS: Contrary to the perception of the relative safety of waterpipe smoking, this meta-analysis provides quantitative estimates of its association with cancers of the head and neck, esophagus and lung. The scarcity and limited quality of available reports point out the need for larger carefully designed studies in well-defined populations.

KW - Humans

KW - Neoplasms/etiology

KW - Risk

KW - Smoking/adverse effects

KW - Tobacco Products/adverse effects

KW - Water

U2 - 10.1007/s00038-016-0856-2

DO - 10.1007/s00038-016-0856-2

M3 - Article

VL - 62

SP - 73

EP - 83

JO - Sozial- und Praventivmedizin

JF - Sozial- und Praventivmedizin

SN - 1661-8556

IS - 1

ER -