Cancer stem cells and tumor angiogenesis

Domenico Ribatti

Research output: Contribution to journalArticlepeer-review


Cancer stem cells (CSCs) have been identified in several human solid and hematological tumors. They are able to initiate tumor formation and metastasis and express specific cell surface markers. CSC tend to be more resistant to chemotherapeutic agents and radiation therapy than more mature cell types from the same tissue because of increased expression of antiapoptotic proteins. In this context, the development of agents that eliminate or control CSC may be an effective strategy for cancer prevention.

Original languageEnglish
Pages (from-to)13-17
Number of pages5
JournalCancer Letters
Issue number1
Publication statusPublished - Aug 1 2012


  • Angiogenesis
  • Cancer stem cell
  • Tumor growth

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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