Cancer stem cells and tumor angiogenesis

Domenico Ribatti

Research output: Contribution to journalArticlepeer-review

Abstract

Cancer stem cells (CSCs) have been identified in several human solid and hematological tumors. They are able to initiate tumor formation and metastasis and express specific cell surface markers. CSC tend to be more resistant to chemotherapeutic agents and radiation therapy than more mature cell types from the same tissue because of increased expression of antiapoptotic proteins. In this context, the development of agents that eliminate or control CSC may be an effective strategy for cancer prevention.

Original languageEnglish
Pages (from-to)13-17
Number of pages5
JournalCancer Letters
Volume321
Issue number1
DOIs
Publication statusPublished - Aug 1 2012

Keywords

  • Angiogenesis
  • Cancer stem cell
  • Tumor growth

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Fingerprint

Dive into the research topics of 'Cancer stem cells and tumor angiogenesis'. Together they form a unique fingerprint.

Cite this