Candesartan and renal protection: More than blocking angiotensin type 1 receptor?

Daniela Macconi, Giuseppe Remuzzi

Research output: Contribution to journalArticlepeer-review

Abstract

Chen et al. show that candesartan (Cand) displays an antioxidant action independent of angiotensin type 1 receptor (AT1R) blockade that translates into a superior renoprotection of chronic renal inflammation. The peculiarity of Cand in combining AT1R-blocking activity and an antioxidant action could have important theoretical implications for therapy.

Original languageEnglish
Pages (from-to)1112-1114
Number of pages3
JournalKidney International
Volume74
Issue number9
DOIs
Publication statusPublished - Nov 2008

ASJC Scopus subject areas

  • Nephrology

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