Candesartan and renal protection: More than blocking angiotensin type 1 receptor?

Daniela Macconi; Giuseppe Remuzzi

doi:10.1038/ki.2008.420

Candesartan and renal protection: More than blocking angiotensin type 1 receptor?

Daniela Macconi, Giuseppe Remuzzi

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

Chen et al. show that candesartan (Cand) displays an antioxidant action independent of angiotensin type 1 receptor (AT1R) blockade that translates into a superior renoprotection of chronic renal inflammation. The peculiarity of Cand in combining AT1R-blocking activity and an antioxidant action could have important theoretical implications for therapy.

Original language	English
Pages (from-to)	1112-1114
Number of pages	3
Journal	Kidney International
Volume	74
Issue number	9
DOIs	https://doi.org/10.1038/ki.2008.420
Publication status	Published - Nov 2008

ASJC Scopus subject areas

Nephrology

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