Candida Africana: Is it a fungal pathogen?

Orazio Romeo, Hans Jürgen Tietz, Giuseppe Criseo

Research output: Contribution to journalArticle

Abstract

Twelve years ago, Candida africana was proposed as new species within the Candida albicans species complex, and since then has raised much controversy regarding whether or not it should be considered a separate species from C. albicans. Although its taxonomic status is still a matter of debate, this yeast differs from C. albicans by a number of phenotypic, genotypic, pathogenic and clinical characteristics that make this fungus particularly interesting to study. Current epidemiological and clinical data suggest that C. africana has a worldwide distribution, is particularly adapted to colonize/infect human vaginal mucosa, and may also be responsible for most serious diseases involving other human organs. In this review, we will discuss the current knowledge about C. africana, highlighting its role in human infections, thus providing a complete clinical picture in order to understand if this yeast can be considered an important pathogen.

Original languageEnglish
Pages (from-to)192-197
Number of pages6
JournalCurrent Fungal Infection Reports
Volume7
Issue number3
DOIs
Publication statusPublished - Sep 2013

Keywords

  • Antifungals
  • Atypical Candida strains
  • Candida africana
  • Candida albicans
  • Candida dubliniensis
  • Candidiasis
  • Chlamydospore negative
  • Epidemiology
  • Molecular identification
  • Vaginal infections
  • Vaginitis

ASJC Scopus subject areas

  • Infectious Diseases

Fingerprint Dive into the research topics of 'Candida Africana: Is it a fungal pathogen?'. Together they form a unique fingerprint.

  • Cite this