Candida glabrata and pre-term premature rupture of membrane complicating in vitro pregnancy: Case report and confirmation of mother to neonate transmission

Alessandro Alfei, Annalisa Rizzo, C. Cavanna, F. Lallitto, A. Spinillo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Case report: We report a case of Candida glabrata infection in an in vitro fertilization-assisted pregnancy complicated by pre-term pre-labor rupture of the membranes. We found C. glabrata in gastric fluid, amniotic fluid and maternal vaginal swab. Neonatal and maternal isolates showed indistinguishable molecular patterns analyzed by fingerprint DNA multilocus. Discussion: Strong consideration should be given to perform a screening test C. glabrata. Multiple treatments, even in pregnancy, should be considered in women who have positive cultures results.

Original languageEnglish
Pages (from-to)211-214
Number of pages4
JournalArchives of Gynecology and Obstetrics
Volume290
Issue number2
DOIs
Publication statusPublished - 2014

Fingerprint

Candida glabrata
Rupture
Mothers
Newborn Infant
Pregnancy
Membranes
DNA Fingerprinting
Fertilization in Vitro
Amniotic Fluid
Stomach
Infection
In Vitro Techniques
Therapeutics

Keywords

  • Candida glabrata
  • Fingerprint
  • Micafungin
  • pPROM
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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AU - Cavanna, C.

AU - Lallitto, F.

AU - Spinillo, A.

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AB - Case report: We report a case of Candida glabrata infection in an in vitro fertilization-assisted pregnancy complicated by pre-term pre-labor rupture of the membranes. We found C. glabrata in gastric fluid, amniotic fluid and maternal vaginal swab. Neonatal and maternal isolates showed indistinguishable molecular patterns analyzed by fingerprint DNA multilocus. Discussion: Strong consideration should be given to perform a screening test C. glabrata. Multiple treatments, even in pregnancy, should be considered in women who have positive cultures results.

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