Abstract
Candida overgrowth in gastric juice of peptic ulcer subjects under therapy with H2-receptor (H2-R) antagonists has been detected in 21.4 and 53.8% of cases after short- and long-term treatment respectively, and in 8 % of controls. Both types of H2-R antagonists, ranitidine and cimetidine, were equally associated with production of yeasts. The location of ulcers, whether gastric or duodenal, seems to have no influence on fungal growth. Females were more susceptible than males to develop Candida in gastric juice. In the short-term course with H2-R blockers fungal colonization of gastric juice was associated with delay of the rate of ulcer healing. Fungal detection in gastric juice was not associated with mucosal invasion by Candida since in none of the patients who had a biopsy for gastric ulcer was Candida detected by histology.
| Original language | English |
|---|---|
| Pages (from-to) | 158-163 |
| Number of pages | 6 |
| Journal | Digestion |
| Volume | 28 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1983 |
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Keywords
- Candida
- Cimetidine
- Gastric juice
- H<inf>2</inf>-receptor antagonists
- Peptic ulcer
ASJC Scopus subject areas
- Gastroenterology
Cite this
Candida overgrowth in gastric juice of peptic ulcer subjects on short- and long-term treatment with h2-receptor antagonists. / Boero, M.; Pera, A.; Andriulli, A.; Ponti, V.; Canepa, G.; Palmas, F.; Duglio, A.; Molinaro, G. C.; Toselli, M.; Riccardino, N.
In: Digestion, Vol. 28, No. 3, 1983, p. 158-163.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Candida overgrowth in gastric juice of peptic ulcer subjects on short- and long-term treatment with h2-receptor antagonists
AU - Boero, M.
AU - Pera, A.
AU - Andriulli, A.
AU - Ponti, V.
AU - Canepa, G.
AU - Palmas, F.
AU - Duglio, A.
AU - Molinaro, G. C.
AU - Toselli, M.
AU - Riccardino, N.
PY - 1983
Y1 - 1983
N2 - Candida overgrowth in gastric juice of peptic ulcer subjects under therapy with H2-receptor (H2-R) antagonists has been detected in 21.4 and 53.8% of cases after short- and long-term treatment respectively, and in 8 % of controls. Both types of H2-R antagonists, ranitidine and cimetidine, were equally associated with production of yeasts. The location of ulcers, whether gastric or duodenal, seems to have no influence on fungal growth. Females were more susceptible than males to develop Candida in gastric juice. In the short-term course with H2-R blockers fungal colonization of gastric juice was associated with delay of the rate of ulcer healing. Fungal detection in gastric juice was not associated with mucosal invasion by Candida since in none of the patients who had a biopsy for gastric ulcer was Candida detected by histology.
AB - Candida overgrowth in gastric juice of peptic ulcer subjects under therapy with H2-receptor (H2-R) antagonists has been detected in 21.4 and 53.8% of cases after short- and long-term treatment respectively, and in 8 % of controls. Both types of H2-R antagonists, ranitidine and cimetidine, were equally associated with production of yeasts. The location of ulcers, whether gastric or duodenal, seems to have no influence on fungal growth. Females were more susceptible than males to develop Candida in gastric juice. In the short-term course with H2-R blockers fungal colonization of gastric juice was associated with delay of the rate of ulcer healing. Fungal detection in gastric juice was not associated with mucosal invasion by Candida since in none of the patients who had a biopsy for gastric ulcer was Candida detected by histology.
KW - Candida
KW - Cimetidine
KW - Gastric juice
KW - H<inf>2</inf>-receptor antagonists
KW - Peptic ulcer
UR - http://www.scopus.com/inward/record.url?scp=0021043856&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021043856&partnerID=8YFLogxK
U2 - 10.1159/000198980
DO - 10.1159/000198980
M3 - Article
C2 - 6141973
AN - SCOPUS:0021043856
VL - 28
SP - 158
EP - 163
JO - Digestion
JF - Digestion
SN - 0012-2823
IS - 3
ER -