Canine mastocytoma: Report of 8 cases diagnosed by fine needle cytology and clinicopathologic correlations

Franco Fulciniti, Diana Di Mattia, Maria Pia Curcio, Patrizia Bove, Anna Maria Rota, Gerardo Botti

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Mast cell proliferations are commoner in dogs than in humans; mass forming lesions in the former are apt to fine needle sampling and the obtained cytopathological picture might be informing to enhance recognition of similar proliferations in humans. Case: Clinical and cytopathologic data were collected from 8 cases of canine mastocytomas diagnosed by fine needle cytology. The cytopathologic presentation was correlated with the individual therapy performed and with the clinical stage. In all cases the cytopathological diagnosis was confirmed by histopathologic examination of the excised mass, by necropsy or by response to therapy. Conclusion: There are marked similarities between canine and human mastocytomas, despite possible differences in the clinical course of the disease in both species. Canine mastocytomas may hence be used as an animal model of a human disease and, as such, familiarity with their cytologic presentation may be useful for recognizing mast cell proliferations in humans.

Original languageEnglish
Pages (from-to)616-620
Number of pages5
JournalActa Cytologica
Volume51
Issue number4
Publication statusPublished - 2007

Keywords

  • Dog diseases
  • Fine needle biopsy
  • Mastocytoma

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

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