Capability of myocardial revascularization to modify late potentials in old myocardial infarction

M. S. Negroni, C. Klersy, V. Marchiano, L. Menicanti, A. Frigiola, M. Chimienti, L. De Ambroggi

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Ventricular late potentials (LP) recorded on the body surface in pts with old myocardial infarction (MI) are considered to reflect slow conduction, due to the presence in the infarct border zone of fibers of viable myocardium within ischemic and scarring tissue. To assess whether myocardial revascularization could influence the electrophysiologic dishomogeneity responsible for the occurrence of LP, 80 pts, 75 males and 5 females, aged 55 ± 9 yrs, with old MI (anterior in 24, inferior in 37 anterior and inferior in 5 and non Q in 14 pts), undergoing surgery, were studied. A Marquette Mac15 HiRes ECG recorder was used to identify LP before and after surgery; 250 beats (X, Y and Z Frank leads) were averaged and filtered at 40-250 Hz. Statistical analysis was performed, using logistic regression, to determine the significance of several selected covariates simultaneously. LP were present in 28 pts (35%) before surgery and disappeared in 11 of them (39%) thereafter. Persistence of LP after surgery was related to the presence of an inferior MI and of a ventricular aneurysm. These data suggest that revascularization is able to determine disappearance of LP, probably due to functional recovery of perinecrotic hibernated myocardium. In particular anatomic conditions (inferior MI, left ventricle aneurysm) this functional recovery seems not to be sufficient for the disappearance of LP.

Original languageEnglish
Pages (from-to)519-522
Number of pages4
JournalNew Trends in Arrhythmias
Issue number4
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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