Capecitabine cardiac toxicity presenting as effort angina: A case report

Chiara Lestuzzi, Diana Crivellari, Fausto Rigo, Elda Viel, Nereo Meneguzzo

Research output: Contribution to journalArticlepeer-review


We report a case of capecitabine-induced cardiotoxicity (effort angina) in a woman with metastatic breast carcinoma. Due to cancer progression, rechallenge of therapy with capecitabine was attempted, using several strategies in order to prevent cardiotoxicity. The most (even if not fully) effective strategy was reducing capecitabine dosage together with nitrates, calcium-channel blockers and trimetazidine therapy.

Original languageEnglish
Pages (from-to)700-703
Number of pages4
JournalJournal of Cardiovascular Medicine
Issue number9
Publication statusPublished - Sep 2010


  • angina
  • capecitabine
  • cardiotoxicity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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