Carbon dioxide rebreathing during noninvasive mechanical ventilation

Francesco Mojoli; Antonio Braschi

doi:10.1007/978-3-642-11365-9_12

Carbon dioxide rebreathing during noninvasive mechanical ventilation

Francesco Mojoli, Antonio Braschi

IRCCS Fondazione Policlinico San Matteo

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Partial reinhalation of previously exhaled carbon dioxide (CO₂) may impair the efficacy of noninvasive mechanical ventilation (NIMV) in improving CO₂ removal and unloading ventilatory muscles [1]. At constant alveolar ventilation, any CO₂ concentration above zero in inhaled gases causes an increase of arterial CO₂ tension by an equal amount. Accordingly, significant CO₂ rebreathing increases alveolar ventilation requirements to maintain desired arterial CO₂ tension. This can limit the beneficial effects of inspiratory assistance provided by NIMV. In this chapter, we review general mechanisms of CO₂ rebreathing and the effect of different interfaces, respiratory circuits, and ventilator settings.

Original language	English
Title of host publication	Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications
Publisher	Springer Berlin Heidelberg
Pages	77-82
Number of pages	6
ISBN (Print)	9783642113642
DOIs	https://doi.org/10.1007/978-3-642-11365-9_12
Publication status	Published - 2010

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-642-11365-9_12

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abstract = "Partial reinhalation of previously exhaled carbon dioxide (CO2) may impair the efficacy of noninvasive mechanical ventilation (NIMV) in improving CO2 removal and unloading ventilatory muscles [1]. At constant alveolar ventilation, any CO2 concentration above zero in inhaled gases causes an increase of arterial CO2 tension by an equal amount. Accordingly, significant CO2 rebreathing increases alveolar ventilation requirements to maintain desired arterial CO2 tension. This can limit the beneficial effects of inspiratory assistance provided by NIMV. In this chapter, we review general mechanisms of CO2 rebreathing and the effect of different interfaces, respiratory circuits, and ventilator settings.",

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AB - Partial reinhalation of previously exhaled carbon dioxide (CO2) may impair the efficacy of noninvasive mechanical ventilation (NIMV) in improving CO2 removal and unloading ventilatory muscles [1]. At constant alveolar ventilation, any CO2 concentration above zero in inhaled gases causes an increase of arterial CO2 tension by an equal amount. Accordingly, significant CO2 rebreathing increases alveolar ventilation requirements to maintain desired arterial CO2 tension. This can limit the beneficial effects of inspiratory assistance provided by NIMV. In this chapter, we review general mechanisms of CO2 rebreathing and the effect of different interfaces, respiratory circuits, and ventilator settings.

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ER -

Carbon dioxide rebreathing during noninvasive mechanical ventilation

Abstract

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