Carboxyethyl γ-aminobutyric acid, a polyamine derivative molecule with a growth effect on hybridomas

Antonella Cerino, Mara De Amici, Fernando F. Fussi, Giulia C.B. Astaldi Ricotti

Research output: Contribution to journalArticle

Abstract

An increased proliferation of hybridomas is induced by a polyamine derivative molecule, CEGABA (carboxyethyl gamma-aminobutyric acid). The effects of CEGABA and CR-ECGS (endothelial cell growth supplement) on hybridoma growth are similar. However, both factors are less efficient than HECS (human endothelial culture supernatant) in inducing hybridoma growth through all the steps of hybridoma production, including: recovery after fusion, cloning, and proliferation.

Original languageEnglish
Pages (from-to)229-235
Number of pages7
JournalJournal of Immunological Methods
Volume77
Issue number2
DOIs
Publication statusPublished - Mar 18 1985

Keywords

  • CEGABA
  • growth factors
  • hybridoma cultures
  • media supplements

ASJC Scopus subject areas

  • Biotechnology
  • Immunology

Fingerprint Dive into the research topics of 'Carboxyethyl γ-aminobutyric acid, a polyamine derivative molecule with a growth effect on hybridomas'. Together they form a unique fingerprint.

  • Cite this