Carcinosarcoma of the uterus: A clinicopathological multicenter CTF study

Enrico Sartori, Luca Bazzurini, Angiolo Gadducci, Fabio Landoni, Andrea Lissoni, Tiziano Maggino, Paolo Zola, Beniamino La Face

Research output: Contribution to journalArticle

Abstract

The purpose of this paper is to retrospectively analyze the clinical and pathological data of 118 cases of uterine carcinosarcoma. Prognostic factors and management were evaluated. χ2 and log-rank tests were performed. Surgical stage at time of surgery was the most important prognostic factor (P <0.0001); in stage I-II disease depth of myometrial invasion and lymphatic/vascular space involvement were significantly related to outcome, whereas other factors were not useful. In stage I-II patients postoperative radiation did not improve 5-year disease-free survival. Survival curves in patients with advanced disease treated with cisplatin-containing regimens or with doxorubicin (without cisplatin)-containing regimens were overlapping.

Original languageEnglish
Pages (from-to)70-75
Number of pages6
JournalGynecologic Oncology
Volume67
Issue number1
DOIs
Publication statusPublished - Oct 1997

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

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    Sartori, E., Bazzurini, L., Gadducci, A., Landoni, F., Lissoni, A., Maggino, T., Zola, P., & La Face, B. (1997). Carcinosarcoma of the uterus: A clinicopathological multicenter CTF study. Gynecologic Oncology, 67(1), 70-75. https://doi.org/10.1006/gyno.1997.4827