Cardiac autonomic function and sensitivity to pain in postmenopausal women with angina and normal coronary arteries

Gaetano Antonio Lanza, Vincenzo Pasceri, Giuseppe Colonna, Francesco Cucinelli, Antonio Fortini, Antonio Lanzone, Filippo Crea, Attilio Maseri

Research output: Contribution to journalArticlepeer-review

Abstract

An increased sensitivity to painful stimuli and an abnormal cardiac autonomic function have previously been reported in patients with angina and angiographically normal coronary arteries, a syndrome that mainly affects postmenopausal women. In this study we compared both general sensitivity to pain, by evaluating time to forearm ischemic pain (FIP) provoked by sphygmomanometer cuff inflation, and cardiac autonomic function, by measuring heart rate variability (HRV), and QT and QT(c) intervals on 24-hour Holter recordings, in 25 postmenopausal women with angina and normal coronary arteries and in 22 healthy postmenopausal women. Compared with controls, patients had a reproducible strikingly lower time to FIP (149 ± 121 vs 295 ± 158 seconds, p

Original languageEnglish
Pages (from-to)1174-1179
Number of pages6
JournalThe American Journal of Cardiology
Volume79
Issue number9
DOIs
Publication statusPublished - May 1 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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